Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS030768-05
Application #
2268729
Study Section
AIDS and Related Research Study Section 7 (ARRG)
Project Start
1992-03-16
Project End
1997-02-28
Budget Start
1996-02-29
Budget End
1997-02-28
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Neurology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Parkinson, J F; Mitrovic, B; Merrill, J E (1997) The role of nitric oxide in multiple sclerosis. J Mol Med 75:174-86
Merrill, J E; Murphy, S P; Mitrovic, B et al. (1997) Inducible nitric oxide synthase and nitric oxide production by oligodendrocytes. J Neurosci Res 48:372-84
Mitrovic, B; Ignarro, L J; Vinters, H V et al. (1995) Nitric oxide induces necrotic but not apoptotic cell death in oligodendrocytes. Neuroscience 65:531-9
Koka, P; He, K; Zack, J A et al. (1995) Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha, and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain. J Exp Med 182:941-51
St Pierre, B A; Granger, D A; Wong, J L et al. (1995) A study on tumor necrosis factor, tumor necrosis factor receptors, and nitric oxide in human fetal glial cultures. Adv Pharmacol 34:415-38
Merrill, J E; Jonakait, G M (1995) Interactions of the nervous and immune systems in development, normal brain homeostasis, and disease. FASEB J 9:611-8
Koka, P; He, K; Camerini, D et al. (1995) The mapping of HIV-1 gp160 epitopes required for interleukin-1 and tumor necrosis factor alpha production in glial cells. J Neuroimmunol 57:179-91
Mitrovic, B; St Pierre, B A; Mackenzie-Graham, A J et al. (1994) The role of nitric oxide in glial pathology. Ann N Y Acad Sci 738:436-46
Mackenzie-Graham, A J; Mitrovic, B; Smoll, A et al. (1994) Differential sensitivity to nitric oxide in immortalized, cloned murine oligodendrocyte cell lines. Dev Neurosci 16:162-71
Mitrovic, B; Ignarro, L J; Montestruque, S et al. (1994) Nitric oxide as a potential pathological mechanism in demyelination: its differential effects on primary glial cells in vitro. Neuroscience 61:575-85

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