Neurotoxicity of HIV Peptides in Perinatal Brain

Silverstein, Faye S.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS031054-03
• Application #: 2269030
• Study Section: AIDS and Related Research Study Section 7 (ARRG)
• Project Start: 1993-12-01
• Project End: 1997-11-30
• Budget Start: 1995-12-01
• Budget End: 1996-11-30
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Michigan Ann Arbor
• Department: Pediatrics
• Type: Schools of Medicine
• DUNS #: 791277940
• City: Ann Arbor
• State: MI
• Country: United States
• Zip Code: 48109

Publications

Cowell, Rita M; Xu, Haiyan; Galasso, John M et al. (2002) Hypoxic-ischemic injury induces macrophage inflammatory protein-1alpha expression in immature rat brain. Stroke 33:795-801

Galasso, J M; Liu, Y; Szaflarski, J et al. (2000) Monocyte chemoattractant protein-1 is a mediator of acute excitotoxic injury in neonatal rat brain. Neuroscience 101:737-44

Galasso, J M; Wang, P; Martin, D et al. (2000) Inhibition of TNF-alpha can attenuate or exacerbate excitotoxic injury in neonatal rat brain. Neuroreport 11:231-5

Galasso, J M; Stegman, L D; Blaivas, M et al. (2000) Experimental gliosarcoma induces chemokine receptor expression in rat brain. Exp Neurol 161:85-95

Wang, P; Barks, J D; Silverstein, F S (1999) Tat, a human immunodeficiency virus-1-derived protein, augments excitotoxic hippocampal injury in neonatal rats. Neuroscience 88:585-97

Silverstein, F S (1999) Expanding the scope of child neurology for the 21st century. Curr Opin Neurol 12:133-6

Szaflarski, J; Ivacko, J; Liu, X H et al. (1998) Excitotoxic injury induces monocyte chemoattractant protein-1 expression in neonatal rat brain. Brain Res Mol Brain Res 55:306-14

Galasso, J M; Harrison, J K; Silverstein, F S (1998) Excitotoxic brain injury stimulates expression of the chemokine receptor CCR5 in neonatal rats. Am J Pathol 153:1631-40

Ivacko, J; Szaflarski, J; Malinak, C et al. (1997) Hypoxic-ischemic injury induces monocyte chemoattractant protein-1 expression in neonatal rat brain. J Cereb Blood Flow Metab 17:759-70

Barks, J D; Liu, X H; Sun, R et al. (1997) gp120, a human immunodeficiency virus-1 coat protein, augments excitotoxic hippocampal injury in perinatal rats. Neuroscience 76:397-409