Pathogenesis of Retroviral Neurologic Disease

Sharpe, Arlene H.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS031065-04
• Application #: 2269041
• Study Section: AIDS and Related Research Study Section 3 (ARRC)
• Project Start: 1992-07-01
• Project End: 1997-06-30
• Budget Start: 1995-07-01
• Budget End: 1997-06-30
• Support Year: 4
• Fiscal Year: 1995

Institution

• Name: Brigham and Women's Hospital
• DUNS #: 071723621
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02115

Publications

Lynch, W P; Sharpe, A H (2000) Differential glycosylation of the Cas-Br-E env protein is associated with retrovirus-induced spongiform neurodegeneration. J Virol 74:1558-65

Lynch, W P; Sharpe, A H; Snyder, E Y (1999) Neural stem cells as engraftable packaging lines can mediate gene delivery to microglia: evidence from studying retroviral env-related neurodegeneration. J Virol 73:6841-51

Lynch, W P; Snyder, E Y; Qualtiere, L et al. (1996) Late virus replication events in microglia are required for neurovirulent retrovirus-induced spongiform neurodegeneration: evidence from neural progenitor-derived chimeric mouse brains. J Virol 70:8896-907