Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS031282-04
Application #
2883661
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Program Officer
Jacobs, Tom P
Project Start
1996-03-01
Project End
2001-02-28
Budget Start
1999-03-01
Budget End
2000-02-29
Support Year
4
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Neurosciences
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Tanaka, Hidenobu; Yokota, Hidenori; Jover, Teresa et al. (2004) Ischemic preconditioning: neuronal survival in the face of caspase-3 activation. J Neurosci 24:2750-9
Colbourne, Frederick; Grooms, Sonja Y; Zukin, R Suzanne et al. (2003) Hypothermia rescues hippocampal CA1 neurons and attenuates down-regulation of the AMPA receptor GluR2 subunit after forebrain ischemia. Proc Natl Acad Sci U S A 100:2906-10
Calderone, Agata; Jover, Teresa; Noh, Kyung-min et al. (2003) Ischemic insults derepress the gene silencer REST in neurons destined to die. J Neurosci 23:2112-21
Tanaka, Hidenobu; Calderone, Agata; Jover, Teresa et al. (2002) Ischemic preconditioning acts upstream of GluR2 down-regulation to afford neuroprotection in the hippocampal CA1. Proc Natl Acad Sci U S A 99:2362-7
Jover, Teresa; Tanaka, Hidenobu; Calderone, Agata et al. (2002) Estrogen protects against global ischemia-induced neuronal death and prevents activation of apoptotic signaling cascades in the hippocampal CA1. J Neurosci 22:2115-24
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Skeberdis, V A; Lan, J; Zheng, X et al. (2001) Insulin promotes rapid delivery of N-methyl-D- aspartate receptors to the cell surface by exocytosis. Proc Natl Acad Sci U S A 98:3561-6
Oguro, K; Jover, T; Tanaka, H et al. (2001) Global ischemia-induced increases in the gap junctional proteins connexin 32 (Cx32) and Cx36 in hippocampus and enhanced vulnerability of Cx32 knock-out mice. J Neurosci 21:7534-42
Skeberdis, V A; Lan, J; Opitz, T et al. (2001) mGluR1-mediated potentiation of NMDA receptors involves a rise in intracellular calcium and activation of protein kinase C. Neuropharmacology 40:856-65
Lan , J Y; Skeberdis, V A; Jover, T et al. (2001) Activation of metabotropic glutamate receptor 1 accelerates NMDA receptor trafficking. J Neurosci 21:6058-68

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