Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS031488-04
Application #
2269407
Study Section
AIDS and Related Research Study Section 7 (ARRG)
Program Officer
Kerza-Kwiatecki, a P
Project Start
1993-02-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1998-01-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Neurology
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Minagar, Alireza; Shapshak, Paul; Fujimura, Robert et al. (2002) The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis. J Neurol Sci 202:13-23
Shapshak, Paul; Stewart, Renee V; Rodriguez de la Vega, Pura et al. (2002) Brain macrophage surface marker expression with HIV-1 infection and drug abuse: a preliminary study. J NeuroAIDS 2:37-50
Shapshak, P; Segal, D M; Crandall, K A et al. (1999) Independent evolution of HIV type 1 in different brain regions. AIDS Res Hum Retroviruses 15:811-20
Bradley, W G; Shapshak, P; Delgado, S et al. (1998) Morphometric analysis of the peripheral neuropathy of AIDS. Muscle Nerve 21:1188-95
Delgado, S; Shapshak, P; Stewart, R et al. (1998) Heterogeneity of macrophage and T cell subpopulations in peripheral nerves from HIV infected individuals: A preliminary study. J NeuroAIDS 2:79-97
Segal, D M; Shapshak, P; Zhang, B T et al. (1997) Novel tetrameric tip motifs (APGK and VPGK) in the V3 loop of HIV type 1 envelope sequences in blood and brain from two injection drug users in Miami, Florida. AIDS Res Hum Retroviruses 13:1643-6
Bradley, W G; Verma, A (1996) Painful vasculitic neuropathy in HIV-1 infection: relief of pain with prednisone therapy. Neurology 47:1446-51
Nagano, I; Shapshak, P; Yoshioka, M et al. (1996) Parvalbumin and calbindin D-28 k immunoreactivity in dorsal root ganglia in acquired immunodeficiency syndrome. Neuropathol Appl Neurobiol 22:293-301
Nagano, I; Shapshak, P; Yoshioka, M et al. (1996) Increased NADPH-diaphorase reactivity and cytokine expression in dorsal root ganglia in acquired immunodeficiency syndrome. J Neurol Sci 136:117-28
Fiala, M; Rhodes, R H; Shapshak, P et al. (1996) Regulation of HIV-1 infection in astrocytes: expression of Nef, TNF-alpha and IL-6 is enhanced in coculture of astrocytes with macrophages. J Neurovirol 2:158-66

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