Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS031528-04
Application #
2269459
Study Section
Neurology A Study Section (NEUA)
Project Start
1993-05-01
Project End
1999-07-31
Budget Start
1996-08-09
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Neurology
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Jacobs, Bart C; Koga, Michiaki; van Rijs, Wouter et al. (2008) Subclass IgG to motor gangliosides related to infection and clinical course in Guillain-Barre syndrome. J Neuroimmunol 194:181-90
Nachamkin, I; Arzarte Barbosa, P; Barbosa, P Arzate et al. (2007) Patterns of Guillain-Barre syndrome in children: results from a Mexican population. Neurology 69:1665-71
Perera, Viraj N; Nachamkin, Irving; Ung, Huong et al. (2007) Molecular mimicry in Campylobacter jejuni: role of the lipo-oligosaccharide core oligosaccharide in inducing anti-ganglioside antibodies. FEMS Immunol Med Microbiol 50:27-36
Boffey, Judith; Odaka, Masaaki; Nicoll, Dawn et al. (2005) Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire. J Neuroimmunol 165:92-103
Leonard 2nd, Edward E; Tompkins, Lucy S; Falkow, Stanley et al. (2004) Comparison of Campylobacter jejuni isolates implicated in Guillain-Barre syndrome and strains that cause enteritis by a DNA microarray. Infect Immun 72:1199-203
Boffey, Judith; Nicholl, Dawn; Wagner, Eric R et al. (2004) Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes. J Neuroimmunol 152:98-111
Magira, Eleni E; Papaioakim, Miltiadis; Nachamkin, Irving et al. (2003) Differential distribution of HLA-DQ beta/DR beta epitopes in the two forms of Guillain-Barre syndrome, acute motor axonal neuropathy and acute inflammatory demyelinating polyneuropathy (AIDP): identification of DQ beta epitopes associated with susceptibil J Immunol 170:3074-80
Bowes, Tyrone; Wagner, Eric R; Boffey, Judith et al. (2002) Tolerance to self gangliosides is the major factor restricting the antibody response to lipopolysaccharide core oligosaccharides in Campylobacter jejuni strains associated with Guillain-Barre syndrome. Infect Immun 70:5008-18
Gong, Y; Tagawa, Y; Lunn, M P T et al. (2002) Localization of major gangliosides in the PNS: implications for immune neuropathies. Brain 125:2491-506
Nachamkin, Irving; Liu, Jirong; Li, Ming et al. (2002) Campylobacter jejuni from patients with Guillain-Barre syndrome preferentially expresses a GD(1a)-like epitope. Infect Immun 70:5299-303

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