Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS031775-04
Application #
2269727
Study Section
Neurology C Study Section (NEUC)
Project Start
1992-08-05
Project End
1997-07-31
Budget Start
1995-08-15
Budget End
1997-07-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Washington
Department
Neurosurgery
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Garden, Gwenn A; Libby, Randell T; Fu, Ying-Hui et al. (2002) Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice. J Neurosci 22:4897-905
Pal, Deb K; Greenberg, David A (2002) Evaluating genetic heterogeneity in complex disorders. Hum Hered 53:216-26
Morrison, R S; Kinoshita, Y (2000) The role of p53 in neuronal cell death. Cell Death Differ 7:868-79
Kuntz 4th, C; Kinoshita, Y; Beal, M F et al. (2000) Absence of p53: no effect in a transgenic mouse model of familial amyotrophic lateral sclerosis. Exp Neurol 165:184-90
Johnson, M D; Kinoshita, Y; Xiang, H et al. (1999) Contribution of p53-dependent caspase activation to neuronal cell death declines with neuronal maturation. J Neurosci 19:2996-3006
Yamada, S M; Yamaguchi, F; Brown, R et al. (1999) Suppression of glioblastoma cell growth following antisense oligonucleotide-mediated inhibition of fibroblast growth factor receptor expression. Glia 28:66-76
Johnson, M D; Xiang, H; London, S et al. (1998) Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons. J Neurosci Res 54:721-33
Xiang, H; Kinoshita, Y; Knudson, C M et al. (1998) Bax involvement in p53-mediated neuronal cell death. J Neurosci 18:1363-73
Xiang, H; Hochman, D W; Saya, H et al. (1996) Evidence for p53-mediated modulation of neuronal viability. J Neurosci 16:6753-65
Morrison, R S; Wenzel, H J; Kinoshita, Y et al. (1996) Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death. J Neurosci 16:1337-45

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