Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS031829-04
Application #
2269780
Study Section
Sensory Disorders and Language Study Section (CMS)
Project Start
1993-08-31
Project End
1997-09-29
Budget Start
1995-07-01
Budget End
1997-09-29
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Upstate Medical University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
058889106
City
Syracuse
State
NY
Country
United States
Zip Code
13210
Kelly, Emily A; Tremblay, Marie-Eve; McCasland, James S et al. (2010) Postsynaptic deregulation in GAP-43 heterozygous mouse barrel cortex. Cereb Cortex 20:1696-707
Donovan, Stacy L; McCasland, James S (2008) GAP-43 is critical for normal targeting of thalamocortical and corticothalamic, but not trigeminothalamic axons in the whisker barrel system. Somatosens Mot Res 25:33-47
McIlvain, Vera; McCasland, James S (2006) GAP-43 heterozygous mice show delayed barrel patterning, differentiation of radial glia, and downregulation of GAP-43. Anat Rec A Discov Mol Cell Evol Biol 288:143-57
Dubroff, J G; Stevens, R T; Hitt, J et al. (2006) Anomalous functional organization of barrel cortex in GAP-43 deficient mice. Neuroimage 29:1040-8
Dubroff, J G; Stevens, R T; Hitt, J et al. (2005) Use-dependent plasticity in barrel cortex: intrinsic signal imaging reveals functional expansion of spared whisker representation into adjacent deprived columns. Somatosens Mot Res 22:25-35
McIlvain, Vera A; Robertson, Douglas R; Maimone, Margaret M et al. (2003) Abnormal thalamocortical pathfinding and terminal arbors lead to enlarged barrels in neonatal GAP-43 heterozygous mice. J Comp Neurol 462:252-64
Maier, Donna L; Grieb, Ginny M; Stelzner, Dennis J et al. (2003) Large-scale plasticity in barrel cortex following repeated whisker trimming in young adult hamsters. Exp Neurol 184:737-45
Donovan, Stacy L; Mamounas, Laura A; Andrews, Anne M et al. (2002) GAP-43 is critical for normal development of the serotonergic innervation in forebrain. J Neurosci 22:3543-52
Shen, Yiping; Mani, Shyamala; Donovan, Stacy L et al. (2002) Growth-associated protein-43 is required for commissural axon guidance in the developing vertebrate nervous system. J Neurosci 22:239-47
Maier, D L; Mani, S; Donovan, S L et al. (1999) Disrupted cortical map and absence of cortical barrels in growth-associated protein (GAP)-43 knockout mice. Proc Natl Acad Sci U S A 96:9397-402

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