Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS031907-03
Application #
2269857
Study Section
Diagnostic Radiology Study Section (RNM)
Project Start
1993-08-01
Project End
1997-07-31
Budget Start
1995-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Mach, R H; Wu, L; West, T et al. (1999) The analgesic tropane analogue (+/-)-SM 21 has a high affinity for sigma2 receptors. Life Sci 64:PL131-7
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Mach, R H; Voytko, M L; Ehrenkaufer, R L et al. (1997) Imaging of cholinergic terminals using the radiotracer [18F](+)-4-fluorobenzyltrozamicol: in vitro binding studies and positron emission tomography studies in nonhuman primates. Synapse 25:368-80
Mach, R H; Smith, C R; al-Nabulsi, I et al. (1997) Sigma 2 receptors as potential biomarkers of proliferation in breast cancer. Cancer Res 57:156-61
Mach, R H; Nader, M A; Ehrenkaufer, R L et al. (1997) Use of positron emission tomography to study the dynamics of psychostimulant-induced dopamine release. Pharmacol Biochem Behav 57:477-86
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Efange, S M; Mach, R H; Smith, C R et al. (1995) Vesamicol analogues as sigma ligands. Molecular determinants of selectivity at the vesamicol receptor. Biochem Pharmacol 49:791-7
Mach, R H; Smith, C R; Childers, S R (1995) Ibogaine possesses a selective affinity for sigma 2 receptors. Life Sci 57:PL57-62
Mach, R H; Ehrenkaufer, R L; Greenberg, J H et al. (1995) PET imaging studies of dopamine D2 receptors: comparison of [18F]N-methylspiperone and the benzamide analogues [18F]MABN and [18F]MBP in baboon brain. Synapse 19:177-87