Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS032103-04
Application #
2270086
Study Section
Special Emphasis Panel (ZRG1-NEUB-1 (02))
Program Officer
Jacobs, Tom P
Project Start
1993-08-01
Project End
1997-11-30
Budget Start
1996-09-15
Budget End
1997-11-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Surgery
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Black, Keith L; Yin, Dali; Ong, John M et al. (2008) PDE5 inhibitors enhance tumor permeability and efficacy of chemotherapy in a rat brain tumor model. Brain Res 1230:290-302
Hu, Jinwei; Yuan, Xiangpeng; Ko, MinHee K et al. (2007) Calcium-activated potassium channels mediated blood-brain tumor barrier opening in a rat metastatic brain tumor model. Mol Cancer 6:22
Black, Keith L; Ningaraj, Nagendra S (2004) Modulation of brain tumor capillaries for enhanced drug delivery selectively to brain tumor. Cancer Control 11:165-73
Ningaraj, Nagendra S; Rao, Mamatha K; Black, Keith L (2003) Adenosine 5'-triphosphate-sensitive potassium channel-mediated blood-brain tumor barrier permeability increase in a rat brain tumor model. Cancer Res 63:8899-911
Ningaraj, Nagendra S; Rao, Mamatha; Black, Keith L (2003) Calcium-dependent potassium channels as a target protein for modulation of the blood-brain tumor barrier. Drug News Perspect 16:291-8
Asotra, Kamlesh; Ningaraj, Nagendra; Black, Keith L (2003) Measurement of blood-brain and blood-tumor barrier permeabilities with [14C]-labeled tracers. Methods Mol Med 89:177-90
Hashizume, Kazuhiro; Black, Keith L (2002) Increased endothelial vesicular transport correlates with increased blood-tumor barrier permeability induced by bradykinin and leukotriene C4. J Neuropathol Exp Neurol 61:725-35
Uchida, Mikito; Chen, Zutang; Liu, Yunhui et al. (2002) Overexpression of bradykinin type 2 receptors on glioma cells enhances bradykinin-mediated blood-brain tumor barrier permeability increase. Neurol Res 24:739-46
Ningaraj, Nagendra S; Rao, Mamatha; Hashizume, Kazuhiro et al. (2002) Regulation of blood-brain tumor barrier permeability by calcium-activated potassium channels. J Pharmacol Exp Ther 301:838-51
Liu, Y; Hashizume, K; Samoto, K et al. (2001) Repeated, short-term ischemia augments bradykinin-mediated opening of the blood-tumor barrier in rats with RG2 glioma. Neurol Res 23:631-40

Showing the most recent 10 out of 20 publications