Regulation of Myelination by Insulinlike Growth Factors

Mc Morris, F Arthur

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS032394-03
• Application #: 2270557
• Study Section: Neurological Sciences Subcommittee 1 (NLS)
• Program Officer: Kerza-Kwiatecki, a P
• Project Start: 1994-01-01
• Project End: 1997-12-31
• Budget Start: 1996-01-01
• Budget End: 1997-12-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Wistar Institute
• DUNS #: 042250712
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19104

Publications

Mewar, R; McMorris, F A (1997) Expression of insulin-like growth factor-binding protein messenger RNAs in developing rat oligodendrocytes and astrocytes. J Neurosci Res 50:721-8

Wiemelt, A P; Engleka, M J; Skorupa, A F et al. (1997) Immunochemical visualization and quantitation of cyclic AMP in single cells. J Biol Chem 272:31489-95

McMorris, F A; McKinnon, R D (1996) Regulation of oligodendrocyte development and CNS myelination by growth factors: prospects for therapy of demyelinating disease. Brain Pathol 6:313-29

Vemuri, G S; McMorris, F A (1996) Oligodendrocytes and their precursors require phosphatidylinositol 3-kinase signaling for survival. Development 122:2529-37

Shinar, Y; McMorris, F A (1995) Developing oligodendroglia express mRNA for insulin-like growth factor-I, a regulator of oligodendrocyte development. J Neurosci Res 42:516-27