Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS032727-02
Application #
2271110
Study Section
Psychobiology, Behavior, and Neuroscience Review Committee (PBN)
Program Officer
Kitt, Cheryl A
Project Start
1995-08-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Florida
Department
Physiology
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611

  Publications

Kalra, S P (2011) Pivotal role of leptin-hypothalamus signaling in the etiology of diabetes uncovered by gene therapy: a new therapeutic intervention? Gene Ther 18:319-25
Kalra, Satya P (2008) Disruption in the leptin-NPY link underlies the pandemic of diabetes and metabolic syndrome: new therapeutic approaches. Nutrition 24:820-6
Kalra, Satya P (2008) Central leptin insufficiency syndrome: an interactive etiology for obesity, metabolic and neural diseases and for designing new therapeutic interventions. Peptides 29:127-38
Kalra, Satya P (2007) Global life-long health benefits of repression of hypothalamic NPY system by central leptin gene therapy. Curr Top Med Chem 7:1675-81
Kalra, Satya P; Kalra, Pushpa S (2007) To subjugate NPY is to improve the quality of life and live longer. Peptides 28:413-8
Dube, Michael G; Kalra, Satya P; Kalra, Pushpa S (2007) Low abundance of NPY in the hypothalamus can produce hyperphagia and obesity. Peptides 28:475-9
Boghossian, Stephane; Ueno, Naohiko; Dube, Michael G et al. (2007) Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin. Neurobiol Aging 28:1594-604
Ueno, Naohiko; Inui, Akio; Kalra, Pushpa S et al. (2006) Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice. Peptides 27:2332-42
Boghossian, Stephane; Dube, Michael G; Torto, Rita et al. (2006) Hypothalamic clamp on insulin release by leptin-transgene expression. Peptides 27:3245-54
Boghossian, Stephane; Lecklin, Anne; Dube, Michael G et al. (2006) Increased leptin expression in the dorsal vagal complex suppresses adiposity without affecting energy intake and metabolic hormones. Obesity (Silver Spring) 14:1003-9

Showing the most recent 10 out of 57 publications