Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS033008-03
Application #
2271544
Study Section
Experimental Immunology Study Section (EI)
Project Start
1994-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Northwestern University at Chicago
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611

  Publications

Kang, Min H; Jin, Young H; Kim, Byung S (2018) Effects of Keratinocyte-Derived Cytokine (CXCL-1) on the Development of Theiler's Virus-Induced Demyelinating Disease. Front Cell Infect Microbiol 8:9
Kang, Hyun Seok; Myoung, Jinjong; So, Eui Young et al. (2016) Transgenic expression of non-structural genes of Theiler's virus suppresses initial viral replication and pathogenesis of demyelination. J Neuroinflammation 13:133
Jin, Young-Hee; Kim, Byung S (2015) Isolation of CNS-infiltrating and Resident Microglial Cells. Bio Protoc 5:
Hou, Wanqiu; Jin, Young-Hee; Kang, Hyun Seok et al. (2014) Interleukin-6 (IL-6) and IL-17 synergistically promote viral persistence by inhibiting cellular apoptosis and cytotoxic T cell function. J Virol 88:8479-89
Jin, Young-Hee; Hou, Wanqiu; Kang, Hyun Seok et al. (2013) The role of interleukin-6 in the expression of PD-1 and PDL-1 on central nervous system cells following infection with Theiler's murine encephalomyelitis virus. J Virol 87:11538-51
Myoung, Jinjong; Kang, Hyun Seok; Hou, Wanqiu et al. (2012) Epitope-specific CD8+ T cells play a differential pathogenic role in the development of a viral disease model for multiple sclerosis. J Virol 86:13717-28
Jin, Young-Hee; Kang, Hyun Seok; Mohindru, Mani et al. (2011) Preferential induction of protective T cell responses to Theiler's virus in resistant (C57BL/6 x SJL)F1 mice. J Virol 85:3033-40
Jin, Young-Hee; Hou, Wanqiu; Kim, Seung Jae et al. (2010) Type I interferon signals control Theiler's virus infection site, cellular infiltration and T cell stimulation in the CNS. J Neuroimmunol 226:27-37
Kang, Hyun Seok; Kim, Byung S (2010) Predominant clonal accumulation of CD8+ T cells with moderate avidity in the central nervous systems of Theiler's virus-infected C57BL/6 mice. J Virol 84:2774-86
Hou, Wanqiu; Kang, Hyun Seok; Kim, Byung S (2009) Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection. J Exp Med 206:313-28

Showing the most recent 10 out of 52 publications