AIDS and the TH-2 Dominant Immunity of the Normal CNS

Knopf, Paul M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS033070-03
• Application #: 2271630
• Study Section: AIDS and Related Research Study Section 7 (ARRG)
• Project Start: 1994-07-01
• Project End: 1998-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Brown University
• Department: Physiology
• Type: Schools of Medicine
• DUNS #: 001785542
• City: Providence
• State: RI
• Country: United States
• Zip Code: 02912

Publications

Harling-Berg, C J; Park, T J; Knopf, P M (1999) Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulation. J Neuroimmunol 101:111-27

Knopf, P M; Harling-Berg, C J; Cserr, H F et al. (1998) Antigen-dependent intrathecal antibody synthesis in the normal rat brain: tissue entry and local retention of antigen-specific B cells. J Immunol 161:692-701

Gordon, L B; Nolan, S C; Ksander, B R et al. (1998) Normal cerebrospinal fluid suppresses the in vitro development of cytotoxic T cells: role of the brain microenvironment in CNS immune regulation. J Neuroimmunol 88:77-84

Gordon, L B; Nolan, S C; Cserr, H F et al. (1997) Growth of P511 mastocytoma cells in BALB/c mouse brain elicits CTL response without tumor elimination: a new tumor model for regional central nervous system immunity. J Immunol 159:2399-408

Knopf, P M; Cserr, H F; Nolan, S C et al. (1995) Physiology and immunology of lymphatic drainage of interstitial and cerebrospinal fluid from the brain. Neuropathol Appl Neurobiol 21:175-80