Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS033147-02
Application #
2271750
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1995-08-01
Project End
1998-06-30
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Neurosciences
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Hoogland, Tycho M; Saggau, Peter (2004) Facilitation of L-type Ca2+ channels in dendritic spines by activation of beta2 adrenergic receptors. J Neurosci 24:8416-27
McQuiston, A Rory; Saggau, Peter (2003) Mu-opioid receptors facilitate the propagation of excitatory activity in rat hippocampal area CA1 by disinhibition of all anatomical layers. J Neurophysiol 90:1936-48
Faas, Guido C; Adwanikar, Hita; Gereau 4th, Robert W et al. (2002) Modulation of presynaptic calcium transients by metabotropic glutamate receptor activation: a differential role in acute depression of synaptic transmission and long-term depression. J Neurosci 22:6885-90
Xiong, Z Q; Saggau, P; Stringer, J L (2000) Activity-dependent intracellular acidification correlates with the duration of seizure activity. J Neurosci 20:1290-6
Qian, J; Saggau, P (1999) Modulation of transmitter release by action potential duration at the hippocampal CA3-CA1 synapse. J Neurophysiol 81:288-98
Saggau, P; Gray, R; Dani, J A (1999) Optical measurements of calcium signals in mammalian presynaptic terminals. Methods Enzymol 294:3-19
Bullen, A; Saggau, P (1999) High-speed, random-access fluorescence microscopy: II. Fast quantitative measurements with voltage-sensitive dyes. Biophys J 76:2272-87
Qian, J; Saggau, P (1999) Activity-dependent modulation of K+ currents at presynaptic terminals of mammalian central synapses. J Physiol 519 Pt 2:427-37
Sinha, S R; Saggau, P (1999) Simultaneous optical recording of membrane potential and intracellular calcium from brain slices. Methods 18:204-14, 175
Bullen, A; Saggau, P (1998) Indicators and optical configuration for simultaneous high-resolution recording of membrane potential and intracellular calcium using laser scanning microscopy. Pflugers Arch 436:788-96

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