Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
7R01NS033150-02
Application #
2271756
Study Section
Neurology A Study Section (NEUA)
Project Start
1996-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Neurosurgery
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Yan, Hong Q; Shin, Samuel S; Ma, Xiecheng et al. (2014) Differential effect of traumatic brain injury on the nuclear factor of activated T Cells C3 and C4 isoforms in the rat hippocampus. Brain Res 1548:63-72
Bales, James W; Wagner, Amy K; Kline, Anthony E et al. (2009) Persistent cognitive dysfunction after traumatic brain injury: A dopamine hypothesis. Neurosci Biobehav Rev 33:981-1003
Yan, Hong Qu; Ma, Xiecheng; Chen, Xiangbai et al. (2007) Delayed increase of tyrosine hydroxylase expression in rat nigrostriatal system after traumatic brain injury. Brain Res 1134:171-9
Wilson, Margaret S; Chen, Xiangbai; Ma, Xiecheng et al. (2005) Synaptosomal dopamine uptake in rat striatum following controlled cortical impact. J Neurosci Res 80:85-91
Kline, Anthony E; Massucci, Jaime L; Ma, Xiecheng et al. (2004) Bromocriptine reduces lipid peroxidation and enhances spatial learning and hippocampal neuron survival in a rodent model of focal brain trauma. J Neurotrauma 21:1712-22
Kline, Anthony E; Massucci, Jaime L; Dixon, C Edward et al. (2004) The therapeutic efficacy conferred by the 5-HT(1A) receptor agonist 8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) after experimental traumatic brain injury is not mediated by concomitant hypothermia. J Neurotrauma 21:175-85
Dixon, C Edward; Ma, Xiecheng; Kline, Anthony E et al. (2003) Acute etomidate treatment reduces cognitive deficits and histopathology in rats with traumatic brain injury. Crit Care Med 31:2222-7
Kline, Anthony E; Bolinger, Bryan D; Kochanek, Patrick M et al. (2002) Acute systemic administration of interleukin-10 suppresses the beneficial effects of moderate hypothermia following traumatic brain injury in rats. Brain Res 937:22-31
Yan, Hong Qu; Kline, Anthony E; Ma, Xiecheng et al. (2002) Traumatic brain injury reduces dopamine transporter protein expression in the rat frontal cortex. Neuroreport 13:1899-901
Kline, Anthony E; Yu, Jianyun; Massucci, Jaime L et al. (2002) Protective effects of the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin against traumatic brain injury-induced cognitive deficits and neuropathology in adult male rats. Neurosci Lett 333:179-82

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