Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS033356-02
Application #
2272133
Study Section
Neurology A Study Section (NEUA)
Project Start
1995-06-01
Project End
1999-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Yee, R E; Cheng, D W; Huang, S C et al. (2001) Blood-brain barrier and neuronal membrane transport of 6-[18F]fluoro-L-DOPA. Biochem Pharmacol 62:1409-15
Yee, R E; Irwin, I; Milonas, C et al. (2001) Novel observations with FDOPA-PET imaging after early nigrostriatal damage. Mov Disord 16:838-48
Stout, D B; Huang, S C; Namavari, M et al. (2000) Distribution volume of 3-O-methyl-6. J Cereb Blood Flow Metab 20:1717-24
Yee, R E; Huang, S C; Stout, D B et al. (2000) Nigrostriatal reduction of aromatic L-amino acid decarboxylase activity in MPTP-treated squirrel monkeys: in vivo and in vitro investigations. J Neurochem 74:1147-57
Shoghi-Jadid, K; Huang, S C; Stout, D B et al. (2000) Striatal kinetic modeling of FDOPA with a cerebellar-derived constraint on the distribution of volume of 30MFD: a PET investigation using non-human primates. J Cereb Blood Flow Metab 20:1134-48
Petric, A; Barrio, J R; Namavari, M et al. (1999) Synthesis of 3beta-(4-[18F]fluoromethylphenyl)- and 3beta-(2-[18F] fluoromethylphenyl)tropane-2beta-carboxylic acid methyl esters: new ligands for mapping brain dopamine transporter with positron emission tomography. Nucl Med Biol 26:529-35
Huang, S C; Quintana, J; Satyamurthy, N et al. (1999) [18F]Fluoro-beta-fluoromethylene-m-tyrosine derivatives show stereo, geometrical, and regio specificities as in vivo central dopaminergic probes in monkeys. Nucl Med Biol 26:365-70
Lacan, G; Satyamurthy, N; Barrio, J R (1999) Synthesis of stereo (R and S) and geometric (E and Z) isomers of [18F]fluoro-beta-fluoromethylene-m-tyrosine derivatives: in vivo probes of central dopaminergic function. Nucl Med Biol 26:359-63
Stout, D; Petric, A; Satyamurthy, N et al. (1999) 2Beta-carbomethoxy-3beta-(4- and 2-[18F]fluoromethylphenyl)tropanes: specific probes for in vivo quantification of central dopamine transporter sites. Nucl Med Biol 26:897-903
Stout, D B; Huang, S C; Melega, W P et al. (1998) Effects of large neutral amino acid concentrations on 6-[F-18]Fluoro-L-DOPA kinetics. J Cereb Blood Flow Metab 18:43-51

Showing the most recent 10 out of 13 publications