Interleukin 4 Signalling in Astrocytes

Barna, Barbara P.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS033932-02
• Application #: 2272985
• Study Section: Neurology C Study Section (NEUC)
• Project Start: 1995-06-01
• Project End: 1999-05-31
• Budget Start: 1996-06-01
• Budget End: 1997-05-31
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: Cleveland Clinic Lerner
• DUNS #: 017730458
• City: Cleveland
• State: OH
• Country: United States
• Zip Code: 44195

Publications

Barna, B P; Mattera, R; Jacobs, B S et al. (2001) Epidermal growth factor regulates astrocyte expression of the interleukin-4 receptor via a MAPK-independent pathway. Cell Immunol 208:18-24

Liu, J; Estes, M L; Drazba, J A et al. (2000) Anti-sense oligonucleotide of p21(waf1/cip1) prevents interleukin 4-mediated elevation of p27(kip1) in low grade astrocytoma cells. Oncogene 19:661-9

Liu, H; Jacobs, B S; Liu, J et al. (2000) Interleukin-13 sensitivity and receptor phenotypes of human glial cell lines: non-neoplastic glia and low-grade astrocytoma differ from malignant glioma. Cancer Immunol Immunother 49:319-24

Liu, H; Prayson, R A; Estes, M L et al. (2000) In vivo expression of the interleukin 4 receptor alpha by astrocytes in epilepsy cerebral cortex. Cytokine 12:1656-61

Kondo, S; Tanaka, Y; Kondo, Y et al. (1998) Antisense telomerase treatment: induction of two distinct pathways, apoptosis and differentiation. FASEB J 12:801-11

Liu, J; Flanagan, W M; Drazba, J A et al. (1997) The CDK inhibitor, p27Kip1, is required for IL-4 regulation of astrocyte proliferation. J Immunol 159:812-9