Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS034103-01A1
Application #
2273225
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1995-12-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Southern California
Department
Neurology
Type
Schools of Medicine
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089

  Publications

Askanas, Valerie; Engel, W King; Nogalska, Anna (2009) Inclusion body myositis: a degenerative muscle disease associated with intra-muscle fiber multi-protein aggregates, proteasome inhibition, endoplasmic reticulum stress and decreased lysosomal degradation. Brain Pathol 19:493-506
Askanas, Valerie; Engel, W King (2008) Inclusion-body myositis: muscle-fiber molecular pathology and possible pathogenic significance of its similarity to Alzheimer's and Parkinson's disease brains. Acta Neuropathol 116:583-95
Askanas, Valerie; Engel, W King (2007) Inclusion-body myositis, a multifactorial muscle disease associated with aging: current concepts of pathogenesis. Curr Opin Rheumatol 19:550-9
Engel, W King; Askanas, Valerie (2006) Inclusion-body myositis: clinical, diagnostic, and pathologic aspects. Neurology 66:S20-9
Askanas, Valerie; Engel, W King (2006) Inclusion-body myositis: a myodegenerative conformational disorder associated with Abeta, protein misfolding, and proteasome inhibition. Neurology 66:S39-48
Askanas, Valerie; Engel, W King (2003) Unfolding story of inclusion-body myositis and myopathies: role of misfolded proteins, amyloid-beta, cholesterol, and aging. J Child Neurol 18:185-90
Askanas, Valerie; Engel, W King (2003) Proposed pathogenetic cascade of inclusion-body myositis: importance of amyloid-beta, misfolded proteins, predisposing genes, and aging. Curr Opin Rheumatol 15:737-44
Askanas, Valerie; Engel, W King (2002) Newest pathogenetic considerations in inclusion-body myositis: possible role of amyloid-beta, cholesterol, relation to aging and to Alzheimer's disease. Curr Rheumatol Rep 4:427-33
Askanas, Valerie; Engel, W King (2002) Inclusion-body myositis and myopathies: different etiologies, possibly similar pathogenic mechanisms. Curr Opin Neurol 15:525-31
Askanas, V; Engel, W K (2001) Inclusion-body myositis: newest concepts of pathogenesis and relation to aging and Alzheimer disease. J Neuropathol Exp Neurol 60:1-14

Showing the most recent 10 out of 17 publications