Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS034571-06
Application #
2273846
Study Section
Neuropharmacology and Neurochemistry Review Committee (NPNC)
Project Start
1989-09-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Duchemin, Anne-Marie; Neff, Norton H; Hadjiconstantinou, Maria (2010) Aromatic L-amino acid decarboxylase phosphorylation and activation by PKGIalpha in vitro. J Neurochem 114:542-52
Neff, Norton H; Wemlinger, Trina A; Duchemin, Anne-Marie et al. (2006) Clozapine modulates aromatic L-amino acid decarboxylase activity in mouse striatum. J Pharmacol Exp Ther 317:480-7
Duchemin, A M; Berry, M D; Neff, N H et al. (2000) Phosphorylation and activation of brain aromatic L-amino acid decarboxylase by cyclic AMP-dependent protein kinase. J Neurochem 75:725-31
Neff, N H; Wemlinger, T A; Hadjiconstantinou, M (2000) SCH 23390 enhances exogenous L-DOPA decarboxylation in nigrostriatal neurons. J Neural Transm 107:429-43
Goettl, V M; Lindsey, A E; Neff, N H et al. (2000) GM1 ganglioside restores abnormal responses to acute thermal and mechanical stimuli in aged rats. Brain Res 858:380-5
Goettl, V M; Wemlinger, T A; Duchemin, A M et al. (1999) GM1 ganglioside restores dopaminergic neurochemical and morphological markers in aged rats. Neuroscience 92:991-1000
Cho, S; Duchemin, A M; Neff, N H et al. (1999) Tyrosine hydroxylase, aromatic L-amino acid decarboxylase and dopamine metabolism after chronic treatment with dopaminergic drugs. Brain Res 830:237-45
Goettl, V M; Tejwani, G A; Neff, N H et al. (1999) Decreased neuropeptide content in the spinal cord of aged rats: the effect of GM1 ganglioside. Neuroreport 10:513-6
Young, E A; Duchemin, A M; Neff, N H et al. (1998) Parallel modulation of striatal dopamine synthetic enzymes by second messenger pathways. Eur J Pharmacol 357:15-23
Cho, S; Neff, N H; Hadjiconstantinou, M (1997) Regulation of tyrosine hydroxylase and aromatic L-amino acid decarboxylase by dopaminergic drugs. Eur J Pharmacol 323:149-57

Showing the most recent 10 out of 12 publications