Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS034779-02
Application #
2333030
Study Section
Neurology C Study Section (NEUC)
Program Officer
Small, Judy A
Project Start
1996-02-01
Project End
2000-01-31
Budget Start
1997-02-01
Budget End
1998-01-31
Support Year
2
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Cold Spring Harbor Laboratory
Department
Type
DUNS #
065968786
City
Cold Spring Harbor
State
NY
Country
United States
Zip Code
11724
Chiang, Hsueh-Cheng; Wang, Lei; Xie, Zuolei et al. (2010) PI3 kinase signaling is involved in Abeta-induced memory loss in Drosophila. Proc Natl Acad Sci U S A 107:7060-5
de Bivort, Benjamin Lovegren; Guo, Hui-Fu; Zhong, Yi (2009) Notch signaling is required for activity-dependent synaptic plasticity at the Drosophila neuromuscular junction. J Neurogenet 23:395-404
Chiang, Hsueh-Cheng; Iijima, Koichi; Hakker, Inessa et al. (2009) Distinctive roles of different beta-amyloid 42 aggregates in modulation of synaptic functions. FASEB J 23:1969-77
Ho, Ivan Shun; Hannan, Frances; Guo, Hui-Fu et al. (2007) Distinct functional domains of neurofibromatosis type 1 regulate immediate versus long-term memory formation. J Neurosci 27:6852-7
Hannan, Frances; Ho, Ivan; Tong, James Jiayuan et al. (2006) Effect of neurofibromatosis type I mutations on a novel pathway for adenylyl cyclase activation requiring neurofibromin and Ras. Hum Mol Genet 15:1087-98
Guo, Hui-Fu; Zhong, Yi (2006) Requirement of Akt to mediate long-term synaptic depression in Drosophila. J Neurosci 26:4004-14
Zhong, Yi; Wu, Chun-Fang (2004) Neuronal activity and adenylyl cyclase in environment-dependent plasticity of axonal outgrowth in Drosophila. J Neurosci 24:1439-45
Tong, Jiayuan; Hannan, Frances; Zhu, Yinghua et al. (2002) Neurofibromin regulates G protein-stimulated adenylyl cyclase activity. Nat Neurosci 5:95-6
Wang, Y; Wright, N J; Guo, H et al. (2001) Genetic manipulation of the odor-evoked distributed neural activity in the Drosophila mushroom body. Neuron 29:267-76
Hannan, F; Zhong, Y (1999) Second messenger systems underlying plasticity at the neuromuscular junction. Int Rev Neurobiol 43:119-38

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