Role and Regulation of Creb Protein in Oligodendrocytes

Sato-Bigbee, Carmen

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 5R01NS035097-02
• Application #: 2609695
• Study Section: Neurology B Subcommittee 2 (NEUB)
• Program Officer: Kerza-Kwiatecki, a P
• Project Start: 1996-12-01
• Project End: 1999-11-30
• Budget Start: 1997-12-01
• Budget End: 1998-11-30
• Support Year: 2
• Fiscal Year: 1998

Institution

• Name: Virginia Commonwealth University
• Department: Physiology
• Type: Schools of Medicine
• City: Richmond
• State: VA
• Country: United States
• Zip Code: 23298

Publications

Saini, Harsimran S; Gorse, Karen M; Boxer, Linda M et al. (2004) Neurotrophin-3 and a CREB-mediated signaling pathway regulate Bcl-2 expression in oligodendrocyte progenitor cells. J Neurochem 89:951-61

Afshari, Fatemah S; Chu, Annie K; Sato-Bigbee, Carmen (2002) Recovery of adult oligodendrocytes is preceded by a ""lag period"" accompanied by upregulation of transcription factors expressed in developing young cells. J Neurosci Res 67:174-84

Afshari, F S; Chu, A K; Sato-Bigbee, C (2001) Effect of cyclic AMP on the expression of myelin basic protein species and myelin proteolipid protein in committed oligodendrocytes: differential involvement of the transcription factor CREB. J Neurosci Res 66:37-45

Johnson, J R; Chu, A K; Sato-Bigbee, C (2000) Possible role of CREB in the stimulation of oligodendrocyte precursor cell proliferation by neurotrophin-3. J Neurochem 74:1409-17

Sato-Bigbee, C; Pal, S; Chu, A K (1999) Different neuroligands and signal transduction pathways stimulate CREB phosphorylation at specific developmental stages along oligodendrocyte differentiation. J Neurochem 72:139-47