Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS035751-03
Application #
2703120
Study Section
AIDS and Related Research Study Section 7 (ARRG)
Program Officer
Kerza-Kwiatecki, a P
Project Start
1996-07-01
Project End
2003-04-30
Budget Start
1998-05-01
Budget End
1999-04-30
Support Year
3
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Veterinary Sciences
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Caples, Matthew J; Clements, Janice E; Barber, Sheila A (2006) Protein kinase CK2 phosphorylates the Nef protein from a neurovirulent simian immunodeficiency virus. Virology 348:156-64
Carruth, Lucy M; Zink, M Christine; Tarwater, Patrick M et al. (2005) SIV-specific T lymphocyte responses in PBMC and lymphoid tissues of SIV-infected pigtailed macaques during suppressive combination antiretroviral therapy. J Med Primatol 34:109-21
Rue, Sarah M; Roos, Jason W; Tarwater, Patrick M et al. (2005) Phosphorylation and proteolytic cleavage of gag proteins in budded simian immunodeficiency virus. J Virol 79:2484-92
Overholser, Emily D; Babas, Tahar; Zink, M Christine et al. (2005) CD4-independent entry and replication of simian immunodeficiency virus in primary rhesus macaque astrocytes are regulated by the transmembrane protein. J Virol 79:4944-51
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Rue, Sarah M; Roos, Jason W; Amzel, L Mario et al. (2003) Hydrogen bonding at a conserved threonine in lentivirus capsid is required for virus replication. J Virol 77:8009-18
Overholser, Emily D; Coleman, Gary D; Bennett, Jennifer L et al. (2003) Expression of simian immunodeficiency virus (SIV) nef in astrocytes during acute and terminal infection and requirement of nef for optimal replication of neurovirulent SIV in vitro. J Virol 77:6855-66
Weed, Michael R; Hienz, Robert D; Brady, Joseph V et al. (2003) Central nervous system correlates of behavioral deficits following simian immunodeficiency virus infection. J Neurovirol 9:452-64
Shen, Anding; Zink, M Christine; Mankowski, Joseph L et al. (2003) Resting CD4+ T lymphocytes but not thymocytes provide a latent viral reservoir in a simian immunodeficiency virus-Macaca nemestrina model of human immunodeficiency virus type 1-infected patients on highly active antiretroviral therapy. J Virol 77:4938-49
Babas, Tahar; Munoz, Daniel; Mankowski, Joseph L et al. (2003) Role of microglial cells in selective replication of simian immunodeficiency virus genotypes in the brain. J Virol 77:208-16

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