Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS036195-01S1
Application #
2504336
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1997-04-01
Project End
2001-03-31
Budget Start
1997-04-01
Budget End
1998-03-31
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Physiology
Type
Schools of Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Zheleznova, Nadezhda N; Sedelnikova, Anna; Weiss, David S (2009) Function and modulation of delta-containing GABA(A) receptors. Psychoneuroendocrinology 34 Suppl 1:S67-73
Zheleznova, N; Sedelnikova, A; Weiss, D S (2008) alpha1beta2delta, a silent GABAA receptor: recruitment by tracazolate and neurosteroids. Br J Pharmacol 153:1062-71
Torres, Viviana I; Weiss, David S (2002) Identification of a tyrosine in the agonist binding site of the homomeric rho1 gamma-aminobutyric acid (GABA) receptor that, when mutated, produces spontaneous opening. J Biol Chem 277:43741-8
Chang, Yongchang; Ghansah, Emmanuel; Chen, Yonghui et al. (2002) Desensitization mechanism of GABA receptors revealed by single oocyte binding and receptor function. J Neurosci 22:7982-90
Ghansah, E; Weiss, D S (2001) Modulation of GABA(A) receptors by benzodiazepines and barbiturates is autonomous of PKC activation. Neuropharmacology 40:327-33
Filippova, N; Sedelnikova, A; Zong, Y et al. (2000) Regulation of recombinant gamma-aminobutyric acid (GABA)(A) and GABA(C) receptors by protein kinase C. Mol Pharmacol 57:847-56
Filippova, N; Dudley, R; Weiss, D S (1999) Evidence for phosphorylation-dependent internalization of recombinant human rho1 GABAC receptors. J Physiol 518 ( Pt 2):385-99
Wotring, V E; Chang, Y; Weiss, D S (1999) Permeability and single channel conductance of human homomeric rho1 GABAC receptors. J Physiol 521 Pt 2:327-36
Ghansah, E; Weiss, D S (1999) Benzodiazepines do not modulate desensitization of recombinant alpha1beta2gamma2 GABA(A) receptors. Neuroreport 10:817-21