Children who sustain moderate-to-severe traumatic brain injury (TBI) are at high risk for long-term neurobehavioral sequelae. Little is known, however, about the impact of pediatric TBI on families, or the extent to which recovery from TBI is influenced by the family environment. The purpose of the proposed continuation project is to fill this void through extended follow-up of a sample of children who were hospitalizes between the ages of 6-12 years for either TBI or orthopedic injuries not involving CNS insult. The original study was designed to follow children and families over the first post-injury year. Hypothesis 1 was that TBI in this age group has more adverse and enduring effects on families than orthopedic injuries. Hypothesis 2 was that characteristics of the family environment predict child outcomes, even after injury severity and the child's pre-injury behavioral functioning are taken into account. Preliminary findings support both hypotheses and raise questions with regard to the later, adolescent outcomes of TBI compared to orthopedic injuries. In the proposed project, the majority of current study participants will return for three extended follow-up spaced at one-year intervals. The sample will include 41 children and adolescents with severe TBI, 47 with moderate TBI, and 54 with orthopedic injuries. although previous measures will be readministered and hypotheses are unchanged, additional tests of executive function and social reasoning will be given to the children to investigate later-emerging deficits in these areas. Assessments of family outcomes will also be expanded to include measures of sibling adjustment, daily phone diaries of family activities, and direct observations of parent-child interactions. Analysis will focus on group comparisons, changes over time, and predictors of outcome. Results will clarify injury sequelae, shed light on risk and protective factors, and inform efforts to reduce the long-term morbidity of TBI and other traumatic childhood injures.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS036335-01
Application #
2039052
Study Section
Human Development and Aging Subcommittee 3 (HUD)
Program Officer
Broman, Sarah H
Project Start
1997-05-15
Project End
2001-03-31
Budget Start
1997-05-15
Budget End
1998-03-31
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Fay, Taryn B; Yeates, Keith Owen; Wade, Shari L et al. (2009) Predicting longitudinal patterns of functional deficits in children with traumatic brain injury. Neuropsychology 23:271-82
Josie, Katherine Leigh; Peterson, Catherine Cant; Burant, Christopher et al. (2008) Predicting family burden following childhood traumatic brain injury: a cumulative risk approach. J Head Trauma Rehabil 23:357-68
Beebe, Dean W; Krivitzky, Lauren; Wells, Carolyn T et al. (2007) Brief report: parental report of sleep behaviors following moderate or severe pediatric traumatic brain injury. J Pediatr Psychol 32:845-50
Wade, Shari L; Gerry Taylor, H; Yeates, Keith Owen et al. (2006) Long-term parental and family adaptation following pediatric brain injury. J Pediatr Psychol 31:1072-83
Yeates, Keith Owen; Armstrong, Kira; Janusz, Jennifer et al. (2005) Long-term attention problems in children with traumatic brain injury. J Am Acad Child Adolesc Psychiatry 44:574-84
Taylor, H Gerry (2004) Research on outcomes of pediatric traumatic brain injury: current advances and future directions. Dev Neuropsychol 25:199-225
Yeates, Keith Owen; Swift, Erika; Taylor, H Gerry et al. (2004) Short- and long-term social outcomes following pediatric traumatic brain injury. J Int Neuropsychol Soc 10:412-26
Wade, Shari L; Stancin, Terry; Taylor, H Gerry et al. (2004) Interpersonal stressors and resources as predictors of parental adaptation following pediatric traumatic injury. J Consult Clin Psychol 72:776-84
Schwartz, Lisa; Taylor, H Gerry; Drotar, Dennis et al. (2003) Long-term behavior problems following pediatric traumatic brain injury: prevalence, predictors, and correlates. J Pediatr Psychol 28:251-63
Wade, Shari L; Taylor, H Gerry; Drotar, Dennis et al. (2003) Parent-adolescent interactions after traumatic brain injury: their relationship to family adaptation and adolescent adjustment. J Head Trauma Rehabil 18:164-76

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