Mr Spectroscopy to Monitor Haart in HIV Brain Injury

Chang, Linda

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Neurological Disorders and Stroke (NINDS)
• Type: Research Project (R01)
• Project #: 7R01NS038834-05
• Application #: 6889170
• Study Section: Special Emphasis Panel (ZRG1-AARR-5 (01))
• Project Start: 1999-05-01
• Project End: 2005-04-30
• Budget Start: 2004-05-01
• Budget End: 2005-04-30
• Support Year: 5
• Fiscal Year: 2001
• Total Cost: $410,918

Institution

• Name: University of Hawaii
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 121911077
• City: Honolulu
• State: HI
• Country: United States
• Zip Code: 96822

Publications

Schifitto, Giovanni; Navia, Bradford A; Yiannoutsos, Constantin T et al. (2007) Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study. AIDS 21:1877-86

Schifitto, Giovanni; Yiannoutsos, Constantin T; Simpson, David M et al. (2006) A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy. J Neurovirol 12:328-31

Chang, Linda; Ernst, Thomas; Speck, Oliver et al. (2005) Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities. Am J Psychiatry 162:361-9

Yiannoutsos, Constantin T; Ernst, Thomas; Chang, Linda et al. (2004) Regional patterns of brain metabolites in AIDS dementia complex. Neuroimage 23:928-35

Zhong, Kai; Ernst, Thomas (2004) Localized in vivo human 1H MRS at very short echo times. Magn Reson Med 52:898-901

Chang, Linda; Ernst, Thomas; St Hillaire, Coryse et al. (2004) Antiretroviral treatment alters relationship between MCP-1 and neurometabolites in HIV patients. Antivir Ther 9:431-40

Cloak, C C; Chang, L; Ernst, T (2004) Increased frontal white matter diffusion is associated with glial metabolites and psychomotor slowing in HIV. J Neuroimmunol 157:147-52

Ernst, Thomas; Chang, Linda (2004) Effect of aging on brain metabolism in antiretroviral-naive HIV patients. AIDS 18 Suppl 1:S61-7

Ernst, T; Chang, L; Arnold, S (2003) Increased glial metabolites predict increased working memory network activation in HIV brain injury. Neuroimage 19:1686-93

Chang, Linda; Ernst, Thomas; Witt, Mallory D et al. (2003) Persistent brain abnormalities in antiretroviral-naive HIV patients 3 months after HAART. Antivir Ther 8:17-26