Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS041546-01A2S1
Application #
6796999
Study Section
Molecular, Cellular and Developmental Neurosciences 2 (MDCN)
Program Officer
Gwinn, Katrina
Project Start
2003-02-01
Project End
2007-01-31
Budget Start
2003-02-01
Budget End
2004-01-31
Support Year
1
Fiscal Year
2003
Total Cost
$74,000
Indirect Cost
Name
University of Mississippi Medical Center
Department
Neurology
Type
Schools of Medicine
DUNS #
928824473
City
Jackson
State
MS
Country
United States
Zip Code
39216
Vig, Parminder J S; Wei, Jinrong; Shao, Qingmei et al. (2012) Suppression of calbindin-D28k expression exacerbates SCA1 phenotype in a disease mouse model. Cerebellum 11:718-32
Hearst, Scoty M; Lopez, Mariper E; Shao, Qingmei et al. (2010) Dopamine D2 receptor signaling modulates mutant ataxin-1 S776 phosphorylation and aggregation. J Neurochem 114:706-16
Vig, Parminder J S; Shao, Qingmei; Lopez, Maripar E (2009) Glial response to polyglutamine-mediated stress. Biosci Hypotheses 2:148-150
Vig, Parminder J S; Shao, Qingmei; Subramony, S H et al. (2009) Bergmann glial S100B activates myo-inositol monophosphatase 1 and Co-localizes to purkinje cell vacuoles in SCA1 transgenic mice. Cerebellum 8:231-44
Vig, P J S; Wei, J; Shao, Q et al. (2007) Role of tissue transglutaminase type 2 in calbindin-D28k interaction with ataxin-1. Neurosci Lett 420:53-7
Vig, P J S; Subramony, S H; D'Souza, D R et al. (2006) Intranasal administration of IGF-I improves behavior and Purkinje cell pathology in SCA1 mice. Brain Res Bull 69:573-9
Vig, Parminder J S; Lopez, Maripar E; Wei, Jinrong et al. (2006) Glial S100B Positive Vacuoles In Purkinje Cells: Earliest Morphological Abnormality In SCA1 Transgenic Mice. J Neurol Sci Turish 23:166-174
D'Souza, D R; Wei, J; Shao, Q et al. (2006) Tissue transglutaminase crosslinks ataxin-1: possible role in SCA1 pathogenesis. Neurosci Lett 409:5-9