Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS042860-02
Application #
6688321
Study Section
Special Emphasis Panel (ZRG1-BDCN-4 (01))
Program Officer
Utz, Ursula
Project Start
2002-12-15
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$306,720
Indirect Cost

  Institution

Name
University of Arkansas for Medical Sciences
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
122452563
City
Little Rock
State
AR
Country
United States
Zip Code
72205

  Publications

Xu, Jihong; Racke, Michael K; Drew, Paul D (2007) Peroxisome proliferator-activated receptor-alpha agonist fenofibrate regulates IL-12 family cytokine expression in the CNS: relevance to multiple sclerosis. J Neurochem 103:1801-10
Xu, Jihong; Drew, Paul D (2007) Peroxisome proliferator-activated receptor-gamma agonists suppress the production of IL-12 family cytokines by activated glia. J Immunol 178:1904-13
Zhang-Gandhi, Cindy X; Drew, Paul D (2007) Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes. J Neuroimmunol 183:50-9
Racke, Michael K; Gocke, Anne R; Muir, Mark et al. (2006) Nuclear receptors and autoimmune disease: the potential of PPAR agonists to treat multiple sclerosis. J Nutr 136:700-3
Xu, Jihong; Drew, Paul D (2006) 9-Cis-retinoic acid suppresses inflammatory responses of microglia and astrocytes. J Neuroimmunol 171:135-44
Drew, Paul D; Xu, Jihong; Storer, Paul D et al. (2006) Peroxisome proliferator-activated receptor agonist regulation of glial activation: relevance to CNS inflammatory disorders. Neurochem Int 49:183-9
Xu, Jihong; Chavis, Janet A; Racke, Michael K et al. (2006) Peroxisome proliferator-activated receptor-alpha and retinoid X receptor agonists inhibit inflammatory responses of astrocytes. J Neuroimmunol 176:95-105
Xu, Jihong; Storer, Paul D; Chavis, Janet A et al. (2005) Agonists for the peroxisome proliferator-activated receptor-alpha and the retinoid X receptor inhibit inflammatory responses of microglia. J Neurosci Res 81:403-11
Drew, Paul D; Storer, Paul D; Xu, Jihong et al. (2005) Hormone regulation of microglial cell activation: relevance to multiple sclerosis. Brain Res Brain Res Rev 48:322-7
Storer, Paul D; Xu, Jihong; Chavis, Janet A et al. (2005) Cyclopentenone prostaglandins PGA2 and 15-deoxy-delta12,14 PGJ2 suppress activation of murine microglia and astrocytes: implications for multiple sclerosis. J Neurosci Res 80:66-74

Showing the most recent 10 out of 16 publications