Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS043171-02
Application #
6685212
Study Section
Molecular, Cellular and Developmental Neurosciences 2 (MDCN)
Program Officer
Talley, Edmund M
Project Start
2002-12-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$290,700
Indirect Cost
Name
Washington University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Ehmann, Nadine; van de Linde, Sebastian; Alon, Amit et al. (2014) Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states. Nat Commun 5:4650
Valakh, Vera; Naylor, Sarah A; Berns, Dominic S et al. (2012) A large-scale RNAi screen identifies functional classes of genes shaping synaptic development and maintenance. Dev Biol 366:163-71
Graf, Ethan R; Valakh, Vera; Wright, Christina M et al. (2012) RIM promotes calcium channel accumulation at active zones of the Drosophila neuromuscular junction. J Neurosci 32:16586-96
Graf, Ethan R; Heerssen, Heather M; Wright, Christina M et al. (2011) Stathmin is required for stability of the Drosophila neuromuscular junction. J Neurosci 31:15026-34
Daniels, Richard W; Miller, Bradley R; DiAntonio, Aaron (2011) Increased vesicular glutamate transporter expression causes excitotoxic neurodegeneration. Neurobiol Dis 41:415-20
Cheli, Verónica T; Daniels, Richard W; Godoy, Ruth et al. (2010) Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency. Hum Mol Genet 19:861-78
Viquez, Natasha M; Füger, Petra; Valakh, Vera et al. (2009) PP2A and GSK-3beta act antagonistically to regulate active zone development. J Neurosci 29:11484-94
Wairkar, Yogesh P; Toda, Hirofumi; Mochizuki, Hiroaki et al. (2009) Unc-51 controls active zone density and protein composition by downregulating ERK signaling. J Neurosci 29:517-28
Graf, Ethan R; Daniels, Richard W; Burgess, Robert W et al. (2009) Rab3 dynamically controls protein composition at active zones. Neuron 64:663-77
Wairkar, Yogesh P; Fradkin, Lee G; Noordermeer, Jasprina N et al. (2008) Synaptic defects in a Drosophila model of congenital muscular dystrophy. J Neurosci 28:3781-9

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