Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS043240-02
Application #
6685971
Study Section
Molecular, Cellular and Developmental Neurosciences 2 (MDCN)
Program Officer
Stewart, Randall R
Project Start
2002-12-01
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$362,188
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Yusifov, Taleh; Savalli, Nicoletta; Gandhi, Chris S et al. (2008) The RCK2 domain of the human BKCa channel is a calcium sensor. Proc Natl Acad Sci U S A 105:376-81
Savalli, Nicoletta; Kondratiev, Andrei; de Quintana, Sarah Buxton et al. (2007) Modes of operation of the BKCa channel beta2 subunit. J Gen Physiol 130:117-31
Gudzenko, Vadim; Shiferaw, Yohannes; Savalli, Nicoletta et al. (2007) Influence of channel subunit composition on L-type Ca2+ current kinetics and cardiac wave stability. Am J Physiol Heart Circ Physiol 293:H1805-15
Savalli, Nicoletta; Kondratiev, Andrei; Toro, Ligia et al. (2006) Voltage-dependent conformational changes in human Ca(2+)- and voltage-activated K(+) channel, revealed by voltage-clamp fluorometry. Proc Natl Acad Sci U S A 103:12619-24
Haug, Trude; Sigg, Daniel; Ciani, Sergio et al. (2004) Regulation of K+ flow by a ring of negative charges in the outer pore of BKCa channels. Part I: Aspartate 292 modulates K+ conduction by external surface charge effect. J Gen Physiol 124:173-84
Haug, Trude; Olcese, Riccardo; Toro, Ligia et al. (2004) Regulation of K+ flow by a ring of negative charges in the outer pore of BKCa channels. Part II: Neutralization of aspartate 292 reduces long channel openings and gating current slow component. J Gen Physiol 124:185-97