Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS043254-02
Application #
6681868
Study Section
Molecular, Cellular and Developmental Neurosciences 2 (MDCN)
Program Officer
Gwinn, Katrina
Project Start
2002-12-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$342,912
Indirect Cost
Name
University of Iowa
Department
Pharmacology
Type
Schools of Medicine
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Jin, Zhigang; Chung, Jin Wei; Mei, Wenyan et al. (2015) Regulation of nuclear-cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt. Mol Biol Cell 26:1160-73
Merrill, Ronald A; Slupe, Andrew M; Strack, Stefan (2013) N-terminal phosphorylation of protein phosphatase 2A/B?2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival. FEBS J 280:662-73
Wilson, Theodore J; Slupe, Andrew M; Strack, Stefan (2013) Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease. Neurobiol Dis 51:13-26
Oberg, Elizabeth A; Nifoussi, Shanna K; Gingras, Anne-Claude et al. (2012) Selective proteasomal degradation of the B'? subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15. J Biol Chem 287:43378-89
Ulrich, Jason D; Kim, Man-Su; Houlihan, Patrick R et al. (2012) Distinct activation properties of the nuclear factor of activated T-cells (NFAT) isoforms NFATc3 and NFATc4 in neurons. J Biol Chem 287:37594-609
Strack, Stefan; Cribbs, J Thomas (2012) Allosteric modulation of Drp1 mechanoenzyme assembly and mitochondrial fission by the variable domain. J Biol Chem 287:10990-1001
Slupe, Andrew M; Merrill, Ronald A; Strack, Stefan (2011) Determinants for Substrate Specificity of Protein Phosphatase 2A. Enzyme Res 2011:398751
Dickey, Audrey S; Strack, Stefan (2011) PKA/AKAP1 and PP2A/B?2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics. J Neurosci 31:15716-26
Lu, Yuan; Zha, Xiang-ming; Kim, Eun Young et al. (2011) A kinase anchor protein 150 (AKAP150)-associated protein kinase A limits dendritic spine density. J Biol Chem 286:26496-506
Merrill, Ronald A; Dagda, Ruben K; Dickey, Audrey S et al. (2011) Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1. PLoS Biol 9:e1000612

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