Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS043345-02
Application #
6688947
Study Section
Special Emphasis Panel (ZRG1-BDCN-2 (01))
Program Officer
Stewart, Randall R
Project Start
2002-12-15
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$284,050
Indirect Cost

  Institution

Name
University of Utah
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112

  Publications

Baker, Carrie; Sturt, Brianne L; Bamber, Bruce A (2010) Multiple roles for the first transmembrane domain of GABAA receptor subunits in neurosteroid modulation and spontaneous channel activity. Neurosci Lett 473:242-7
Davis, Kathleen M; Sturt, Brianne L; Friedmann, Andrew J et al. (2010) Regulated lysosomal trafficking as a mechanism for regulating GABAA receptor abundance at synapses in Caenorhabditis elegans. Mol Cell Neurosci 44:307-17
Twede, Vernon; Tartaglia, Anthony L; Covey, Douglas F et al. (2007) The neurosteroids dehydroepiandrosterone sulfate and pregnenolone sulfate inhibit the UNC-49 GABA receptor through a common set of residues. Mol Pharmacol 72:1322-9
Rowland, Aaron M; Richmond, Janet E; Olsen, Jason G et al. (2006) Presynaptic terminals independently regulate synaptic clustering and autophagy of GABAA receptors in Caenorhabditis elegans. J Neurosci 26:1711-20
Bamber, Bruce A; Rowland, Aaron M (2006) Shaping cellular form and function by autophagy. Autophagy 2:247-9
Wardell, Bryan; Marik, Purba S; Piper, David et al. (2006) Residues in the first transmembrane domain of the Caenorhabditis elegans GABA(A) receptor confer sensitivity to the neurosteroid pregnenolone sulfate. Br J Pharmacol 148:162-72