Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS043396-02
Application #
6683614
Study Section
Special Emphasis Panel (ZRG1-MDCN-4 (01))
Program Officer
Talley, Edmund M
Project Start
2002-12-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$201,174
Indirect Cost
Name
University of Pittsburgh
Department
Neurology
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Luo, Fujun; Dittrich, Markus; Cho, Soyoun et al. (2015) Transmitter release is evoked with low probability predominately by calcium flux through single channel openings at the frog neuromuscular junction. J Neurophysiol 113:2480-9
Luo, Fujun; Dittrich, Markus; Stiles, Joel R et al. (2011) Single-pixel optical fluctuation analysis of calcium channel function in active zones of motor nerve terminals. J Neurosci 31:11268-81
Meunier, Frederic A; Nguyen, Tam H; Colasante, Cesare et al. (2010) Sustained synaptic-vesicle recycling by bulk endocytosis contributes to the maintenance of high-rate neurotransmitter release stimulated by glycerotoxin. J Cell Sci 123:1131-40
DeStefino, N R; Pilato, A A; Dittrich, M et al. (2010) (R)-roscovitine prolongs the mean open time of unitary N-type calcium channel currents. Neuroscience 167:838-49
Keith, Ryan K; Poage, Robert E; Yokoyama, Charles T et al. (2007) Bidirectional modulation of transmitter release by calcium channel/syntaxin interactions in vivo. J Neurosci 27:265-9
King Jr, J Darwin; Meriney, Stephen D (2005) Proportion of N-type calcium current activated by action potential stimuli. J Neurophysiol 94:3762-70
Wachman, Elliot S; Poage, Robert E; Stiles, Joel R et al. (2004) Spatial Distribution of Calcium Entry Evoked by Single Action Potentials within the Presynaptic Active Zone. J Neurosci 24:2877-85