Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS043459-02
Application #
6697323
Study Section
Special Emphasis Panel (ZRG1-MDCN-6 (01))
Program Officer
Mitler, Merrill
Project Start
2003-01-15
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$284,000
Indirect Cost
Name
Morehouse School of Medicine
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
102005451
City
Atlanta
State
GA
Country
United States
Zip Code
30310
Tosini, Gianluca; Owino, Sharon; Guillaume, Jean-Luc et al. (2014) Understanding melatonin receptor pharmacology: latest insights from mouse models, and their relevance to human disease. Bioessays 36:778-87
Baba, Kenkichi; Benleulmi-Chaachoua, Abla; Journé, Anne-Sophie et al. (2013) Heteromeric MT1/MT2 melatonin receptors modulate photoreceptor function. Sci Signal 6:ra89
Tosini, Gianluca; Baba, Kenkichi; Hwang, Christopher K et al. (2012) Melatonin: an underappreciated player in retinal physiology and pathophysiology. Exp Eye Res 103:82-9
Baba, Kenkichi; Mazzoni, Francesca; Owino, Sharon et al. (2012) Age-related changes in the daily rhythm of photoreceptor functioning and circuitry in a melatonin-proficient mouse strain. PLoS One 7:e37799
Peachey, Neal S; Ray, Thomas A; Florijn, Ralph et al. (2012) GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness. Am J Hum Genet 90:331-9
Tosini, Gianluca; Ye, Keqiang; Iuvone, P Michael (2012) N-acetylserotonin: neuroprotection, neurogenesis, and the sleepy brain. Neuroscientist 18:645-53
Alcantara-Contreras, Susana; Baba, Kenkichi; Tosini, Gianluca (2011) Removal of melatonin receptor type 1 increases intraocular pressure and retinal ganglion cells death in the mouse. Neurosci Lett 494:61-4
Sompol, Pradoldej; Liu, Xia; Baba, Kenkichi et al. (2011) N-acetylserotonin promotes hippocampal neuroprogenitor cell proliferation in sleep-deprived mice. Proc Natl Acad Sci U S A 108:8844-9
Sengupta, Anamika; Baba, Kenkichi; Mazzoni, Francesca et al. (2011) Localization of melatonin receptor 1 in mouse retina and its role in the circadian regulation of the electroretinogram and dopamine levels. PLoS One 6:e24483
Pinotti, Mirko; Bertolucci, Cristiano; Frigato, Elena et al. (2010) Chronic sleep deprivation markedly reduces coagulation factor VII expression. Haematologica 95:1429-32

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