Recurrent pediatric headache is a chronic pain syndrome affecting more than two million American children and often resulting in significant functional disability and debilitation. Moreover, this syndrome represents a substantial cost to the patient's family and the health care system. The goal of the present study is to evaluate the efficacy of a new cost-effective approach to the treatment of recurrent pediatric headache that allows children to learn how to self-manage their headaches via a CD-ROM program (called """"""""Headstrong TM""""""""). This grant proposal is being submitted in response to PA-01-115, which called for research seeking to identify and refine innovative and effective treatment strategies for specific pain conditions. A randomized trial will be used to evaluate the effectiveness of the Headstrong TM intervention. One-hundred and eight (108) pediatric patients, ages 7-12 years, with a diagnosed recurrent migraine, muscle-contraction, or chronic daily headache syndrome will be enrolled in the study. After enrollment, each patient's baseline headache frequency, duration, and intensity will be assessed for one month using headache diaries. During this one-month baseline period, we will also collect data to examine headache-related disability and health related quality of life. After baseline, patients will be randomly assigned to the standard medical care plus Headstrong TM intervention or the standard medical care plus Education condition (also a CD-ROM program with information about recurrent headaches, such as types, etiology, and triggers). Both groups will work through modules in their respective programs over the course of one month. Dependent measures will then continue to be collected at one-month post-treatment and three-, six-, and twelve-month post-treatment follow-up. The primary study outcome will be headache frequency, duration, and intensity as measured by daily headache diaries. Secondary endpoints will include headache-related disability outcomes and quality of life. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS046641-01A1
Application #
6771435
Study Section
Behavioral Medicine, Interventions and Outcomes Study Section (BMIO)
Program Officer
Porter, Linda L
Project Start
2004-08-01
Project End
2007-07-31
Budget Start
2004-08-01
Budget End
2005-07-31
Support Year
1
Fiscal Year
2004
Total Cost
$220,030
Indirect Cost
Name
University of Kansas
Department
Pediatrics
Type
Schools of Medicine
DUNS #
016060860
City
Kansas City
State
KS
Country
United States
Zip Code
66160
Rapoff, Michael A; Connelly, Mark; Bickel, Jennifer L et al. (2014) Headstrong intervention for pediatric migraine headache: a randomized clinical trial. J Headache Pain 15:12
Karlson, Cynthia W; Litzenburg, Catrina C; Sampilo, Marilyn L et al. (2013) Relationship between daily mood and migraine in children. Headache 53:1624-34
Hershey, Andrew D; Lipton, Richard B (2010) Lifestyles of the young and migrainous. Neurology 75:680-1