Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS047456-01S1
Application #
6867983
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Nunn, Michael
Project Start
2003-09-30
Project End
2007-07-31
Budget Start
2003-09-30
Budget End
2004-07-31
Support Year
1
Fiscal Year
2004
Total Cost
$3,985
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
020520466
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Dowding, J M; Song, W; Bossy, K et al. (2014) Cerium oxide nanoparticles protect against A?-induced mitochondrial fragmentation and neuronal cell death. Cell Death Differ 21:1622-32
Kushnareva, Y E; Gerencser, A A; Bossy, B et al. (2013) Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity. Cell Death Differ 20:353-65
Song, Wenjun; Chen, Jin; Petrilli, Alejandra et al. (2011) Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nat Med 17:377-82
Montessuit, Sylvie; Somasekharan, Syam Prakash; Terrones, Oihana et al. (2010) Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization. Cell 142:889-901
Perkins, Guy; Bossy-Wetzel, Ella; Ellisman, Mark H (2009) New insights into mitochondrial structure during cell death. Exp Neurol 218:183-92
Knott, Andrew B; Bossy-Wetzel, Ella (2009) Nitric oxide in health and disease of the nervous system. Antioxid Redox Signal 11:541-54
Liot, G; Bossy, B; Lubitz, S et al. (2009) Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway. Cell Death Differ 16:899-909
Knott, Andrew B; Bossy-Wetzel, Ella (2008) Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration. Ann N Y Acad Sci 1147:283-92
Gerencser, Akos A; Doczi, Judit; Torocsik, Beata et al. (2008) Mitochondrial swelling measurement in situ by optimized spatial filtering: astrocyte-neuron differences. Biophys J 95:2583-98
Knott, Andrew B; Perkins, Guy; Schwarzenbacher, Robert et al. (2008) Mitochondrial fragmentation in neurodegeneration. Nat Rev Neurosci 9:505-18

Showing the most recent 10 out of 19 publications