Abstract

Inflammation is increasingly recognized to play a central role in atherosclerosis and coronary artery disease, and peripheral blood markers of inflammation have been associated with incident and recurrent cardiac events. The relationship of these potentially modifiable risk markers to prognosis after ischemic stroke is less clear. The proposed study, Levels of Inflammatory Markers in the Treatment of Stroke (LIMITS), is an approved ancillary study to the on-going NINDS-funded Secondary Prevention of

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS050724-03
Application #
7260414
Study Section
Epidemiology of Clinical Disorders and Aging Study Section (ECDA)
Program Officer
Jacobs, Tom P
Project Start
2005-05-25
Project End
2009-04-30
Budget Start
2007-07-01
Budget End
2008-06-30
Support Year
3
Fiscal Year
2007
Total Cost
$293,330
Indirect Cost

  Institution

Name
Columbia University (N.Y.)
Department
Neurology
Type
Schools of Medicine
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032

  Publications

Boehme, Amelia K; McClure, Leslie A; Zhang, Yu et al. (2016) Inflammatory Markers and Outcomes After Lacunar Stroke: Levels of Inflammatory Markers in Treatment of Stroke Study. Stroke 47:659-67
Elkind, Mitchell S V; Luna, Jorge M; McClure, Leslie A et al. (2014) C-reactive protein as a prognostic marker after lacunar stroke: levels of inflammatory markers in the treatment of stroke study. Stroke 45:707-16
Dhamoon, Mandip S; McClure, Leslie A; White, Carole L et al. (2014) Quality of life after lacunar stroke: the Secondary Prevention of Small Subcortical Strokes study. J Stroke Cerebrovasc Dis 23:1131-7
Dhamoon, Mandip S; Moon, Yeseon P; Paik, Myunghee C et al. (2012) Trajectory of functional decline before and after ischemic stroke: the Northern Manhattan Study. Stroke 43:2180-4
Katan, Mira; Elkind, Mitchell S V (2011) Inflammatory and neuroendocrine biomarkers of prognosis after ischemic stroke. Expert Rev Neurother 11:225-39
Willey, Joshua Z; Elkind, Mitchell S V (2011) Stroke: do statins improve outcomes after acute ischemic stroke? Nat Rev Neurol 7:364-5
Dhamoon, Mandip S; Moon, Yeseon Park; Paik, Myunghee C et al. (2011) The inclusion of stroke in risk stratification for primary prevention of vascular events: the Northern Manhattan Study. Stroke 42:2878-82
Elkind, M S V; Luna, J M; Coffey, C S et al. (2010) The Levels of Inflammatory Markers in the Treatment of Stroke study (LIMITS): inflammatory biomarkers as risk predictors after lacunar stroke. Int J Stroke 5:117-25
Elkind, Mitchell S V (2010) Impact of innate inflammation in population studies. Ann N Y Acad Sci 1207:97-106
Elkind, Mitchell S V (2010) Inflammatory mechanisms of stroke. Stroke 41:S3-8

Showing the most recent 10 out of 16 publications