The hypothesis is that the permeation/penetration of moderately volatile and nonvolatile organic compounds through disposable gloves will increase for dextrous robotic hand with moving fingers relative to immobile fingers.
The specific aims are: (1) To select the most conservative robotic hand model that provides the shortest normalized breakthrough and lag times, and highest steady state rate out of 3 different robotic hand systems;(2) To compare the permeation/penetration of the selected compounds through the selected gloves with and without movement and with and without press-on nails at temperatures of 25, 30, 32, 35, and 40 C. The inexpensive robotic hand developed in the Preliminary Studies will be used to evaluate single pure solvents for their permeation characteristics;(3).To determine the mechanism of glove failures. The stretch resistance, penetration resistance, and air permeability of the gloves will allow insight on whether movement affects intrinsic glove resistance properties (using method blank data), or whether the chemical causes initial degradation with subsequent penetration/permeation, or whether the degradation and resulting penetration/ permeation occur on a gradual time scale. (4). To develop a model to link ASTM Method F739-99a Closed Loop data for these chemicals and gloves with whole glove data generated from the robotic hand studies. The compounds that do not have ASTM Method F739-99a permeation data will have that data generated for them to assess if correlations exist between the corresponding parameters from the robotic hand.

Public Health Relevance

This grant application covers the National Occupational Research Agenda item to prevent allergic and irritant dermatitis under the disease and injury classification, In addition it covers the Healthy People 2010 Objective 8 (occupational skin diseases) in the Occupational Health classification.

Agency
National Institute of Health (NIH)
Institute
National Institute for Occupational Safety and Health (NIOSH)
Type
Research Project (R01)
Project #
5R01OH009250-03
Application #
8094254
Study Section
Safety and Occupational Health Study Section (SOH)
Program Officer
Potula, Viji
Project Start
2009-09-01
Project End
2013-08-31
Budget Start
2011-09-01
Budget End
2013-08-31
Support Year
3
Fiscal Year
2011
Total Cost
$343,619
Indirect Cost
Name
University of California Los Angeles
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095