Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Project (R01)
Project #
2R01RR009276-04
Application #
2284569
Study Section
Biochemistry Study Section (BIO)
Project Start
1993-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Austin
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
Austin
State
TX
Country
United States
Zip Code
78712
Woldman, Yakov; Appling, Dean R (2002) A general method for determining the contribution of split pathways in metabolite production in the yeast Saccharomyces cerevisiae. Metab Eng 4:170-81
Holmes, William B; Appling, Dean R (2002) Cloning and characterization of methenyltetrahydrofolate synthetase from Saccharomyces cerevisiae. J Biol Chem 277:20205-13
Li, Y; Holmes, W B; Appling, D R et al. (2000) Initiation of protein synthesis in Saccharomyces cerevisiae mitochondria without formylation of the initiator tRNA. J Bacteriol 182:2886-92
Tibbetts, A S; Appling, D R (2000) Characterization of two 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase isozymes from Saccharomyces cerevisiae. J Biol Chem 275:20920-7
Roje, S; Wang, H; McNeil, S D et al. (1999) Isolation, characterization, and functional expression of cDNAs encoding NADH-dependent methylenetetrahydrofolate reductase from higher plants. J Biol Chem 274:36089-96
Raymond, R K; Kastanos, E K; Appling, D R (1999) Saccharomyces cerevisiae expresses two genes encoding isozymes of methylenetetrahydrofolate reductase. Arch Biochem Biophys 372:300-8
Appling, D R (1999) Genetic approaches to the study of protein-protein interactions. Methods 19:338-49
Tibbetts, A S; Appling, D R (1997) Saccharomyces cerevisiae expresses two genes encoding isozymes of 5-aminoimidazole-4-carboxamide ribonucleotide transformylase. Arch Biochem Biophys 340:195-200
Appling, D R; West, M G (1997) Monofunctional NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae. Methods Enzymol 281:178-88
Appling, D R; Kastanos, E; Pasternack, L B et al. (1997) Use of 13C nuclear magnetic resonance to evaluate metabolic flux through folate one-carbon pools in Saccharomyces cerevisiae. Methods Enzymol 281:218-31

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