Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Project (R01)
Project #
1R01RR011576-01A1
Application #
2040361
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1996-09-30
Project End
2000-09-29
Budget Start
1996-09-30
Budget End
1997-09-29
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Barao, Isabel; Hanash, Alan M; Hallett, William et al. (2006) Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells. Proc Natl Acad Sci U S A 103:5460-5
Zimmerman, Z F; Levy, R B (2006) MiHA reactive CD4 and CD8 T-cells effect resistance to hematopoietic engraftment following reduced intensity conditioning. Am J Transplant 6:2089-98
Zimmerman, Zachary; Shatry, Alwi; Deyev, Vadim et al. (2005) Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necrosis fa Biol Blood Marrow Transplant 11:576-86
Hanash, Alan M; Levy, Robert B (2005) Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation. Blood 105:1828-36
Maeda, Yoshinobu; Levy, Robert B; Reddy, Pavan et al. (2005) Both perforin and Fas ligand are required for the regulation of alloreactive CD8+ T cells during acute graft-versus-host disease. Blood 105:2023-7
Marks, Lianne; Levy, Robert B (2004) The cytotoxic potential of regulatory T cells: what has been learned from gene knockout model systems? Transplantation 77:S19-22
Mammolenti, Michele; Gajavelli, Shyam; Tsoulfas, Pantelis et al. (2004) Absence of major histocompatibility complex class I on neural stem cells does not permit natural killer cell killing and prevents recognition by alloreactive cytotoxic T lymphocytes in vitro. Stem Cells 22:1101-10
Shatry, Alwi M; Jones, Monica; Levy, Robert B (2004) The effect of the spleen on compartmental levels and distribution of donor progenitor cells after syngeneic and allogeneic bone marrow transplants. Stem Cells Dev 13:51-62
Marks, Lianne; Altman, Norman H; Podack, Eckhard R et al. (2004) Donor T cells lacking Fas ligand and perforin retain the capacity to induce severe GvHD in minor histocompatibility antigen mismatched bone-marrow transplantation recipients. Transplantation 77:804-12
Blazar, Bruce R; Levy, Robert B; Mak, Tak W et al. (2004) CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease. J Immunol 173:2933-41

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