The project will aim to strengthen and expand India's Sample Registration System (SRS) to obtain reliable estimates of cause-specific mortality from tobacco smoking and chewing in various parts of India by age, gender and socioeconomic group. The SRS is the primary system for collection of Indian mortality data. It is a large demographic survey to provide annual estimates of birth, death and other fertility and mortality indicators at the national and state level. The SRS consists of 6,671 sample units (4,436 rural and 2,235 urban) covering 1.1 million households and a population of about six million. Sample units are selected from the preceding census frame to be representative of the population. The SRS sampling frame will be soon expanded to over 8,000 units, covering over seven million people. Specific goals of the project are: implementing a validated verbal autopsy instrument in the SRS so as to obtain reliable information on the cause of death (for tobacco as well as numerous other causes); determining past tobacco use for adult deaths and current use from living controls within the dead person's household (so as to provide retrospective case-control data annually); specific addition of questions to the baseline questionnaire of the SRS on tobacco and other risk factors, so as to turn the SRS into a uniquely large, reliable and representative prospective study; and follow-up of deaths by cause of a 1998 Special Fertility and Mortality Survey that obtained data on smoking from about two million adults within the current SRS sampling frame (including one million males of whom 40% would smoke). Pilot studies would begin in Andhra Pradesh, Karnataka, and Tamil Nadu, home to 191 million people and about one in six of the SRS units. The project will build sustained capacity within India's flagship mortality surveillance system to monitor a heterogeneous and growing tobacco epidemic, evaluate the effectiveness of control policies and create reliable information for individuals and policy makers. Specific steps will be taken to translate the research findings for state and national policy makers.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
Research Project (R01)
Project #
5R01TW005991-04
Application #
6927273
Study Section
Special Emphasis Panel (ZCA1-SRRB-Q (M1))
Program Officer
Primack, Aron
Project Start
2002-07-01
Project End
2007-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
4
Fiscal Year
2005
Total Cost
$237,000
Indirect Cost
Name
St. Michael's Hospital
Department
Type
DUNS #
208188391
City
Toronto
State
ON
Country
Canada
Zip Code
M5 1-W8
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Million Death Study Collaborators (2017) Changes in cause-specific neonatal and 1-59-month child mortality in India from 2000 to 2015: a nationally representative survey. Lancet 390:1972-1980
Patra, Jayadeep; Maher, Yurie Izawa; Mishra, Sujata et al. (2016) Effects of body mass index, tobacco smoking, alcohol drinking and solid fuel use on the risk of asthma: Individual Participant Data (IPD) meta-analysis of 175?000 individuals from 51 nationally representative surveys. BMJ Open Respir Res 3:e000121
Fadel, Shaza A; Ram, Usha; Morris, Shaun K et al. (2015) Facility Delivery, Postnatal Care and Neonatal Deaths in India: Nationally-Representative Case-Control Studies. PLoS One 10:e0140448
Patra, Jayadeep; Dikshit, Rajesh; Bhatia, Mehak et al. (2015) HPV-avertable cancer risks in India: a pooled analysis of 9 observational studies. Int J Cancer 136:491-2
Ram, Usha; Jha, Prabhat; Gerland, Patrick et al. (2015) Age-specific and sex-specific adult mortality risk in India in 2014: analysis of 0·27 million nationally surveyed deaths and demographic estimates from 597 districts. Lancet Glob Health 3:e767-75
Patra, Jayadeep; Jha, Prabhat; Rehm, Jürgen et al. (2014) Tobacco smoking, alcohol drinking, diabetes, low body mass index and the risk of self-reported symptoms of active tuberculosis: individual participant data (IPD) meta-analyses of 72,684 individuals in 14 high tuberculosis burden countries. PLoS One 9:e96433
Morris, Shaun K; Awasthi, Shally; Kumar, Rajesh et al. (2013) Measles mortality in high and low burden districts of India: estimates from a nationally representative study of over 12,000 child deaths. Vaccine 31:4655-61
Jagnoor, Jagnoor; Suraweera, Wilson; Keay, Lisa et al. (2012) Unintentional injury mortality in India, 2005: nationally representative mortality survey of 1.1 million homes. BMC Public Health 12:487
Morris, Shaun K; Awasthi, Shally; Khera, Ajay et al. (2012) Rotavirus mortality in India: estimates based on a nationally representative survey of diarrhoeal deaths. Bull World Health Organ 90:720-7

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