Continued smoking among cancer patients is associated with poor survival, a greater risk of disease recurrence and a second primary tumor, reduced treatment efficacy, and greater recovery- related complications. Nevertheless, about 50 percent of patients who smoked prior to diagnosis continue to do so following diagnosis/treatment. Despite evidence that hospital- based smoking cessation interventions improve tobacco abstinence rates, cancer patients have largely been neglected as a target population for smoking cessation treatment and research. This empirical gap is surprising since smoking cessation can improve prognosis and enhance quality of life for cancer patients, and can be uniquely effective when delivered in a medical context. The few studies which have assessed the efficacy of smoking cessation treatments for cancer patients have yielded limited data due to the use of small samples and the failure to address possible psychological determinants of smoking. Thus, guided by the research team's Cognitive-Social Health Information- Processing (C-SHIP) model, and influenced by preliminary studies of predictors of continued smoking among cancer patients, this study proposes to assess the impact of an individualized, cognitive-behavioral smoking cessation intervention for patients with head, neck, or lung cancer. This intervention targets cognitive and emotional variables considered predictive of smoking by cancer patients (i.e., perceived risk, self-efficacy, fatalistic beliefs, pros and cons of quitting, emotional distress). Using a randomized prospective design, the aims to be addressed are:
Aim 1 : To compare an individualized cognitive- behavioral smoking cessation intervention to an AHCPR-consistent, time and attention matched, general health educational treatment for increasing readiness to change (i.e., trans-theoretical model stage measure of intention to quit) and reducing smoking rates (i.e., 30-day point prevalence, number of 24-hour quit attempts, number of cigarettes smoked) in a sample of head, neck, and lung cancer patients;
Aim 2 : To examine psychological mediators of the effects of the cognitive-behavioral treatment, including risk perceptions, self-efficacy, fatalistic beliefs, pros and cons of quitting, and emotional distress. This study will allow for the assessment of the added benefit of a cognitive-behavioral intervention to the AHCPR minimum standard of care. Further, this study will assess the generalizability of the C-SHIP model to the tobacco control area. Lastly, this study will permit the identification of the psychological variables that underlie smoking abstinence among cancer patients. The data garnered from this study should have wide applicability in allowing for informed decisions concerning the implementation of cognitive- behavioral smoking cessation approaches for cancer patients on a broader scale.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Research Grants (R03)
Project #
5R03CA088610-02
Application #
6378183
Study Section
Special Emphasis Panel (ZCA1-GRB-T (M1))
Project Start
2000-08-01
Project End
2003-07-31
Budget Start
2001-08-01
Budget End
2003-07-31
Support Year
2
Fiscal Year
2001
Total Cost
$85,834
Indirect Cost
Name
Fox Chase Cancer Center
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Schnoll, Robert A; Rothman, Randi L; Wielt, Dustin B et al. (2005) A randomized pilot study of cognitive-behavioral therapy versus basic health education for smoking cessation among cancer patients. Ann Behav Med 30:1-11
Schnoll, Robert A; Rothman, Randi L; Lerman, Caryn et al. (2004) Comparing cancer patients who enroll in a smoking cessation program at a comprehensive cancer center with those who decline enrollment. Head Neck 26:278-86
Schnoll, Robert A; Rothman, Randi L; Newman, Holly et al. (2004) Characteristics of cancer patients entering a smoking cessation program and correlates of quit motivation: implications for the development of tobacco control programs for cancer patients. Psychooncology 13:346-58
Schnoll, Robert A; James, Calvin; Malstrom, Michael et al. (2003) Longitudinal predictors of continued tobacco use among patients diagnosed with cancer. Ann Behav Med 25:214-22
Schnoll, Robert A; Bradley, Pamela; Miller, Suzanne M et al. (2003) Psychological issues related to the use of spiral CT for lung cancer early detection. Lung Cancer 39:315-25
Schnoll, Robert A; Malstrom, Michael; James, Calvin et al. (2002) Processes of change related to smoking behavior among cancer patients. Cancer Pract 10:11-9
Schnoll, Robert A; Miller, Suzanne M; Unger, Michael et al. (2002) Characteristics of female smokers attending a lung cancer screening program: a pilot study with implications for program development. Lung Cancer 37:257-65
Schnoll, Robert A; Malstrom, Michael; James, Calvin et al. (2002) Correlates of tobacco use among smokers and recent quitters diagnosed with cancer. Patient Educ Couns 46:137-45
Manne, S; Schnoll, R (2001) Measuring cancer patients' psychological distress and well-being: a factor analytic assessment of the Mental Health Inventory. Psychol Assess 13:99-109
Manne, S; Schnoll, R (2001) Measuring supportive and unsupportive responses during cancer treatment: a factor analytic assessment of the partner responses to cancer inventory. J Behav Med 24:297-321

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