=Regular screening for cervical cancer via the Papanicolaou (Pap) smear and appropriate treatment when indicated can prevent over 90% of cervical cancer mortality. However, many women do not obtain regular Pap smears, and among those who do, a large percentage fail to return for follow-up when notified of abnormality. Consequently, cervical cancer remains one of the most common malignancies in the US today accounts for over 4,000 deaths per year. Among African-American and Hispanic women rate of morbidity and mortality due to cervical cancer are 2 to 7 times that observed among Caucasian women. To decrease mortality due to this disease, clinicians must be able to identify women who are at risk of nonadherence and influence patient behavior. Few data are available to direct clinicians on how to assess patient reliability and little understood about factors that determine women's motivation to adhere to follow-up. The proposed research designed to identify psychological and behavioral determinants of women's motivation to adhere to follow-up recommendations for an abnormal Pap smear. We apply the unified theory of behavior to identify cognitive, normative, affective, environmental and social mechanisms underlying adherence to follow-up. Furthermore, this research is designed to understand sociocultural-based differences in motivation through the use of qualitative and quantitative methods of assessment. We propose to study 585 African-American, Hispanic and white women between 25-50 yeas of age over the course of three phases of research. Using interview survey methodology, the proposed research will yield a rich corpus of qualitative information about the social psychological dynamics of Pap smear follow-up. Phase one is an elicitation study in which we empirically derive the nature and structure of the theory constructs. In phase two, we will develop psychometrically-sound survey instruments for use in a prospective examination of adherence to follow-up. In phase three, we will conduct a prospective pilot investigation of adherence to follow-up to collect preliminary data for a large-scale study in which we use the methodology and measures developed during phases one and two. This research will improve clinical outcomes by identifying women at risk of nonadherence so that clinicians can plan management of the abnormal Pap smear accordingly. Additionally, it will assist in the design of tailored interventions to improve adherence. By informing both clinicians and researchers who are involved with cervical cancer prevention, this research will ultimately reduce the morbidity and mortality due to this disease.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Research Grants (R03)
Project #
1R03CA091686-01
Application #
6344435
Study Section
Special Emphasis Panel (ZCA1-SRRB-Q (J2))
Program Officer
Meissner, Helen I
Project Start
2001-04-01
Project End
2003-03-31
Budget Start
2001-04-01
Budget End
2002-03-31
Support Year
1
Fiscal Year
2001
Total Cost
$74,500
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
Asiedu, Gladys B; Breitkopf, Carmen Radecki; Breitkopf, Daniel M (2014) Perceived risk of cervical cancer among low-income women. J Low Genit Tract Dis 18:304-8
Radecki Breitkopf, Carmen; Pearson, Heidi C (2009) A theory-based approach to understanding follow-up of abnormal Pap tests. J Health Psychol 14:361-71
Rubio, Ruby Navarro; Pearson, Heidi C; Clark, Aubrey A et al. (2007) Satisfaction with care among low-income female outpatients. Psychol Health Med 12:334-45
Breitkopf, Carmen Radecki; Pearson, Heidi C; Breitkopf, Daniel M (2005) Poor knowledge regarding the Pap test among low-income women undergoing routine screening. Perspect Sex Reprod Health 37:78-84
Breitkopf, Carmen Radecki; Catero, Jennifer; Jaccard, James et al. (2004) Psychological and sociocultural perspectives on follow-up of abnormal Papanicolaou results. Obstet Gynecol 104:1347-54