Cancer surveillance research requires accurate estimates of risk factors at the small area level. These risk factors are often obtained from surveys such as the National Health Interview Survey (NHIS), or the Behavioral Risk Factors Surveillance Survey (BRFSS). Unfortunately, no one population-based survey provides ideal prevalence estimates of such risk factors. One strategy is to combine information from multiple surveys, using the complementary strengths of one survey to compensate for the weakness of the other. The NHIS is a nationally representative, face-to-face survey with a high response rate; however, it cannot produce state or sub-state estimates of risk factor prevalence because sample sizes are too small. The BRFSS is a state-level telephone survey that excluded non-telephone households and has a lower response rate, but does provide reasonable sample sizes in all states and many countries. Several methods are available for constructing small-area estimators that combine information from both the NHIS and the BRFSS, including direct estimators, estimators under hierarchical Bayes models and model-assisted estimators. The project will focus on the latter, which includes constructing generalized regression (GREG) estimators using BRFSS data and control totals derived from the NHIS dataset, re-weighting schemes to reduce distance measures between sampled elements in BRFSS and NHIS datasets, and the use of existing and newly developed techniques to smooth the resulting estimates using weighting and small-area smoothing techniques. This approach is particularly promising because, in contrast to other proposed techniques, it can be applied using existing publicly available data.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Research Grants (R03)
Project #
1R03CA101362-01
Application #
6647494
Study Section
Special Emphasis Panel (ZCA1-SRRB-D (J2))
Program Officer
Tiwari, Ram C
Project Start
2003-06-01
Project End
2005-05-31
Budget Start
2003-06-01
Budget End
2004-05-31
Support Year
1
Fiscal Year
2003
Total Cost
$79,250
Indirect Cost
Name
University of Pennsylvania
Department
Biostatistics & Other Math Sci
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104