? Malignancies of the skin are the most common cancers among humans. Non-melanoma skin cancers (NMSC), which include basal cell carcinoma and squamous cell carcinoma, have reached epidemic proportions in the United States and are now a major public health concern. The cervicofacial region is most affected by cutaneous malignancies, with approximately 80 percent of NMSC occurring in the head and neck. ? ? Treatment of cervicofacial skin cancers also is more likely to result in significant patient morbidity, because of the functional and cosmetic importance of this region. Adverse consequences may include physical, functional deficits, as well as, psychosocial issues related to potential disfigurement. Unlike other malignancies, skin cancer has not been well investigated in terms of patient quality of life (QOL) assessment. Furthermore, no validated disease-specific QOL instrument currently exists for skin cancer. ? ? Our proposed study seeks to fill this gap by creating and beginning the initial validation of a disease-specific instrument to measure QOL issues relevant for NMSC patients and initiating the process of determining the QOL of patients with NMSC using the newly developed scale. ? ?

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Research Grants (R03)
Project #
1R03CA108271-01
Application #
6794321
Study Section
Special Emphasis Panel (ZCA1-SRRB-Q (J2))
Program Officer
Jeffery, Diana D
Project Start
2004-05-01
Project End
2006-04-30
Budget Start
2004-05-01
Budget End
2005-04-30
Support Year
1
Fiscal Year
2004
Total Cost
$68,000
Indirect Cost
Name
Medical College of Wisconsin
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
937639060
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Rhee, John S; Davis-Malesevich, Melinda; Logan, Brent R et al. (2008) Behavior modification and risk perception in patients with nonmelanoma skin cancer. WMJ 107:62-8
Rhee, John S; Matthews, B Alex; Neuburg, Marcy et al. (2007) The skin cancer index: clinical responsiveness and predictors of quality of life. Laryngoscope 117:399-405
Rhee, John S; Matthews, B Alex; Neuburg, Marcy et al. (2006) Validation of a quality-of-life instrument for patients with nonmelanoma skin cancer. Arch Facial Plast Surg 8:314-8
Matthews, B Alex; Rhee, John S; Neuburg, Marcy et al. (2006) Development of the facial skin care index: a health-related outcomes index for skin cancer patients. Dermatol Surg 32:924-34; discussion 934
Rhee, John S; Matthews, B Alex; Neuburg, Marcy et al. (2005) Creation of a quality of life instrument for nonmelanoma skin cancer patients. Laryngoscope 115:1178-85