The proposed pilot research is in response to one of NCI's goals of this program announcement, which is to? examine both adverse and positive effects of cancer diagnosis and treatment on patients and families, and to? develop and evaluate interventions to improve quality of life and decrease negative outcomes. This? prospective, longitudinal project seeks to further our understanding of the psychosocial sequelae of head? and neck cancer for both patients and their partners or spouses, using both quantitative and qualitative? methods, and to develop and test the feasibility of a brief couples intervention designed to improve the? couples' well-being, quality of life, and relationship. The uncertainty and life threatening nature of cancer? diagnoses can lead to anxiety, depression, and traumatic stress. Further, head and neck cancer is a? physically and emotionally devastating disease that can cause facial disfigurement, as well as difficulties with? speech, eating, and mobility. This results in poor quality of life. Spouses of patients also experience distress,? caregiver burden, and decreases in their own quality of life. Although behavioral medicine interventions? designed to improve psychological adjustment and quality of life in cancer patients have shown promising? outcomes, head and neck cancer has been understudied in this context and there has been little research on? including spouses in the intervention, or targeting the relationship for intervention.
The specific aims of the? proposed research are to (1) characterize both negative and positive symptoms of adjustment to head and? neck cancer in patients and their partners over time, and to examine the psychosocial pathways in which? relationship-focused coping and relationship quality may affect these symptoms. Negative symptoms? include traumatic stress, depression, and anxiety and positive symptoms include enhanced growth and? quality of life; (2) qualitatively examine the impact of head and neck cancer on patients, partners, and their? relationship; and (3) to evaluate the feasibility of a brief two-session couples intervention to improve quality? of life and relationship quality. Eighty couples (n=160) will be recruited. Distress, traumatic stress, positive? outcomes, coping, relationship quality, and quality of life will be assessed in both patients and partners at? one and six months after cancer diagnosis. Twenty of these couples will also participate in a qualitative? interview. Ten additional couples will be recruited to test the feasibilty of the psychosocial intervention.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Research Grants (R03)
Project #
5R03CA119692-02
Application #
7293598
Study Section
Special Emphasis Panel (ZCA1-SRRB-D (O1))
Program Officer
Jeffery, Diana D
Project Start
2006-09-29
Project End
2009-08-31
Budget Start
2007-09-01
Budget End
2008-08-31
Support Year
2
Fiscal Year
2007
Total Cost
$36,048
Indirect Cost
Name
University of Pittsburgh
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Posluszny, Donna M; Dougall, Angela Liegey; Johnson, Jonas T et al. (2015) Posttraumatic stress disorder symptoms in newly diagnosed patients with head and neck cancer and their partners. Head Neck 37:1282-9