Layman's abstract: Women with a history of preeclampsia in pregnancy are at reduced risk of breast cancer, especially those who delivered a son, not a daughter, from the pregnancy. Why is this so? We compare hormones in the blood of a group of women who had been diagnosed with preeclampsia in pregnancy to hormones in a group who had normal pregnancies, after taking into consideration their age and other factors that influence hormone levels. We hypothesize that women with a history of preeclampsia will have lower estrogens and growth factors related to breast cancer than women who had normal pregnancies.
If we discover that women with a history of preeclampsia have lower estrogens and higher androgens in their blood than women who have had normal pregnancies, then we will have an understanding why women with a history of preeclampsia are at lower risk for breast cancer than others.
| Byberg, Kristine Kjer; Mikalsen, Ingvild Bruun; Eide, Geir Egil et al. (2018) The associations between weight-related anthropometrics during childhood and lung function in late childhood: a retrospective cohort study. BMC Pulm Med 18:10 |
