This proposal is designed to assess the relationship of noninsulin dependent diabetes (NIDDM) and its covariates to macrovascular and microvascular disease in a previously unstudied ethnic cohort by: 1. Providing support to an """"""""under-represented investigator"""""""" Maria Rosario G. Araneta, Ph.D., an epidemiologist of Filipina descent. The present proposal will enable Dr. Araneta the opporunity to gain research experience in diabetes epidemiology, through the mentorship of Dr. Elizabeth Barrett-Connor, and collect and analyze data on which to base a subsequent research grant application on diabetes research. 2. Continuation of the UCSD Filipina Womens Health Study, a cross-sectional study of Filipina women aged 40 and above in San Diego County, through: a) a follow-up telephone interview to determine changes in morbidity, mortality, and medication use since their initial clinical evaluation in 1995-1999, and b) record review validation of reported cardiovascular disease. 3. Conducting statistical analyses of newly obtained data and data from the clinical evaluation to explore the relationship between NIDDM and its covariates, and the metabolic syndrome and its components to macrovascular (cardiovascular and lower extremity arterial disease) and microvascular disease (microalbuminuria, nephropathy, diabetes retinopathy, visual impairment and macular degeneration) among Filipina women.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Research Grants (R03)
Project #
Application #
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Hyde, James F
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of California San Diego
Family Medicine
Schools of Medicine
La Jolla
United States
Zip Code
Bellettiere, John; Kritz-Silverstein, Donna; Laughlin, Gail A et al. (2016) Relation of Depressive Symptoms With Coronary Artery Calcium Determined by Electron-Beam Computed Tomography (from the Rancho Bernardo Study). Am J Cardiol 117:325-32
Armenta, Richard F; Kritz-Silverstein, Donna; Wingard, Deborah et al. (2015) Association of breastfeeding with postmenopausal visceral adiposity among three racial/ethnic groups. Obesity (Silver Spring) 23:475-80
Djibo, Djeneba Audrey; Araneta, Maria Rosario G; Kritz-Silverstein, Donna et al. (2015) Body adiposity index as a risk factor for the metabolic syndrome in postmenopausal Caucasian, African American, and Filipina women. Diabetes Metab Syndr 9:108-13
Shadyab, Aladdin H; Kritz-Silverstein, Donna; Laughlin, Gail A et al. (2015) Ethnic-specific associations of sleep duration and daytime napping with prevalent type 2 diabetes in postmenopausal women. Sleep Med 16:243-9
Araneta, Maria Rosario G; Kanaya, Alka M; Hsu, William C et al. (2015) Optimum BMI cut points to screen asian americans for type 2 diabetes. Diabetes Care 38:814-20
Calvo, Richard Y; Araneta, Maria Rosario G; Kritz-Silverstein, Donna et al. (2014) Relation of serum uric acid to severity and progression of coronary artery calcium in postmenopausal White and Filipino women (from the Rancho Bernardo study). Am J Cardiol 113:1153-8
Medina-Torne, Sheila; Araneta, Maria Rosario G; Macera, Caroline A et al. (2011) Dietary factors associated with adiponectin in Filipino-American women. Ethn Dis 21:190-5
Araneta, Maria Rosario G; Barrett-Connor, Elizabeth (2010) Grand multiparity is associated with type 2 diabetes in Filipino American women, independent of visceral fat and adiponectin. Diabetes Care 33:385-9
Araneta, Maria Rosario G; Grandinetti, Andrew; Chang, Healani K (2010) A1C and diabetes diagnosis among Filipino Americans, Japanese Americans, and Native Hawaiians. Diabetes Care 33:2626-8
Magno, Cheryl P; Araneta, Maria Rosario G; Macera, Caroline A et al. (2008) Cardiovascular disease prevalence, associated risk factors, and plasma adiponectin levels among Filipino American women. Ethn Dis 18:458-63

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