Iodinated disinfection byproducts (DBPs) have recently been detected in US drinking water treatment plants using chloramine, a disinfectant replacement for chlorine that was introduced in order to minimize the formation of the four regulated chloro-bromo trihalomethanes (THMs), which are potential human carcinogens. The iodinated THMs and other DBPs in drinking water are more genotoxic and cytotoxic to mammalian cells than the chloro-bromo counterparts. Therefore, their detection and minimization is crucial to protect public health. Our study aims to validate, in our laboratory, sensitive and specific analytical methods for detection of these compounds, to measure their occurrence in chloraminated drinking waters, to determine the potential for their formation in natural waters treated with emergency disinfection iodine tablets, to measure the ability of granular activated carbon filters to remove iodinated DBPs from water, and to identify the potential human health risk associated with use of iodine tablets as a point-of- use strategy for disinfection of drinking water.

Public Health Relevance

Due to their apparent toxicity to humans, the iodinated disinfection byproducts pose a potential public health risk to (1) military troops or Peace Corps volunteers that rely on iodine tablets or iodinated resin filters for drinking water disinfection for long periods of time and (2) coastal communities with drinking water treatment plants that treat their high iodide source water with chloramine disinfection which transforms the iodide to iodine. Our pilot study aims to measure the occurrence of iodinated DBPs in both cases and to identify the potential human health risk associated with these exposures.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Small Research Grants (R03)
Project #
1R03ES018992-01
Application #
7872544
Study Section
Enabling Bioanalytical and Biophysical Technologies Study Section (EBT)
Program Officer
Heindel, Jerrold
Project Start
2010-04-01
Project End
2012-03-31
Budget Start
2010-04-01
Budget End
2011-03-31
Support Year
1
Fiscal Year
2010
Total Cost
$72,837
Indirect Cost
Name
University of Washington
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195