Infants with perinatal risk factors such as prematurity, perinatal brain injury and/or congenital anomalies are at high risk for permanent disabilities including cerebral palsy, intellectual disability and behavioral disorders, which come at a cost of >$50 billion annually. Early assessments to determine those children at highest risk and/or who have developed permanent disabilities are essential both for clinical care and research studies. Developmental screening is necessary to identify children who require physical, occupational and other interventional therapies and is an important step along the path to maximizing potential in children who are at risk for lifelong disabilities. Gold standard developmental tests, such as the Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III), require an in-person visit to a specialized pediatric center. The Warner Initial Developmental Evaluation of Adaptive and Functional Skills (WIDEA-FS) is a functional developmental assessment that can be completed by telephone in fewer than 20 minutes. The burden of the Bayley-III to families, and research studies is a barrier that could be overcome by implementation of less costly approaches such as the novel WIDEA-FS. Although the WIDEA-FS it has been used successfully in several research studies, it has never been formally compared to a validated developmental evaluation such as the Bailey-III. The proposed cross sectional study to compare the Bayley-III to the WIDEA-FS is essential to validate this rapid, low cost developmental test.

Public Health Relevance

Standardized developmental testing is used for screening and diagnosis of infants who are at risk for developmental disabilities, as well as an outcome measure for research studies. Gold standard developmental tests, such as the Bayley Scales of Infant and Toddler Development, 3rd edition (Bayley-III), require an in- person visit to a specialized pediatric center. The proposed cross sectional study to compare the Bayley-III to the Warner Initial Developmental Evaluation of Adaptive and Functional Skills (WIDEA-FS), which can be administered by telephone, is essential to validate this rapid, low cost developmental test.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Small Research Grants (R03)
Project #
5R03HD090298-02
Application #
9551357
Study Section
National Institute of Child Health and Human Development Initial Review Group (CHHD)
Program Officer
King, Tracy
Project Start
2017-09-01
Project End
2019-08-31
Budget Start
2018-09-01
Budget End
2019-08-31
Support Year
2
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Neurology
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94118
Glass, Hannah C (2018) Hypoxic-Ischemic Encephalopathy and Other Neonatal Encephalopathies. Continuum (Minneap Minn) 24:57-71